#	Pagina
attuale pagina	/open-h2020/projects/224721/index.html

Opendata, web and dolomites

SINERGIA SIGNED

advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse

Total Cost €

EC-Contrib. €

Partnership

Views

SINERGIA project word cloud

Explore the words cloud of the SINERGIA project. It provides you a very rough idea of what is the project "SINERGIA" about.

safety companies innovative members limited failing chip physiology concerted engineering despite efficacy compliancy action drug approximate tissue attrition experts regulatory biotechs ultimately bioengineering discovery screen industrial pipeline imputable drugs advancing unable providers screening lack actors synergistic candidates market unravel organs techniques pathological bioprinting candidate preclinical integrating exist academic of mechanisms efficient physiological technologies relevance validation human network molecule weak predict rational stages dialogue pluripotent closely successfully models cros performances training lab reflect bioreactor meet biotech 3d vitro rates body sinergia oriented diseases tools clinical structured pharma cells microfabrication stem

Project "SINERGIA" data sheet

The following table provides information about the project.

Coordinator	POLITECNICO DI MILANO Organization address address: PIAZZA LEONARDO DA VINCI 32 city: MILANO postcode: 20133 website: www.polimi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Total cost	3˙951˙996 €
EC max contribution	3˙951˙996 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2019
Funding Scheme	MSCA-ITN-ETN
Starting year	2019
Duration (year-month-day)	from 2019-11-01 to 2023-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	POLITECNICO DI MILANO POLITECNICO DI MILANO Organization address address: PIAZZA LEONARDO DA VINCI 32 city: MILANO postcode: 20133 website: www.polimi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	coordinator	522˙999.00
2	Ente Ospedaliero Cantonale Ente Ospedaliero Cantonale Organization address address: Vialle Officina 3 city: Bellinzona postcode: CH-6500 website: http://www.eoc.ch/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (Bellinzona)	participant	562˙553.00
3	UNIVERSITAT BASEL UNIVERSITAT BASEL Organization address address: PETERSPLATZ 1 city: BASEL postcode: 4051 website: www.unibas.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (BASEL)	participant	562˙553.00
4	UNIVERSITEIT MAASTRICHT UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD website: http://www.maastrichtuniversity.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	participant	531˙239.00
5	FAKULTNI NEMOCNICE U SV. ANNY V BRNE FAKULTNI NEMOCNICE U SV. ANNY V BRNE Organization address address: Pekarska 53 city: Brno postcode: 656 91 website: www.fnusa.cz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (Brno)	participant	469˙743.00
6	LIFETEC GROUP BV LIFETEC GROUP BV Organization address address: KENNEDYPLEIN 11 city: EINDHOVEN postcode: 5611 ZS website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (EINDHOVEN)	participant	265˙619.00
7	ACCELERA SRL ACCELERA SRL Organization address address: VIALE PASTEUR 10 city: NERVIANO MI postcode: 20014 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (NERVIANO MI)	participant	261˙499.00
8	BIOMIMX SRL BIOMIMX SRL Organization address address: VIA GIOVANNI DURANDO 38/A city: MILANO postcode: 20158 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	261˙499.00
9	MTTLAB SRL MTTLAB SRL Organization address address: VIA GIACINTO GALLINA 5 city: Trieste postcode: 34132 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Trieste)	participant	261˙499.00
10	UNIVERSITAETSKLINIKUM AACHEN UNIVERSITAETSKLINIKUM AACHEN Organization address address: Pauwelsstrasse 30 city: AACHEN postcode: 52074 website: www.ukaachen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (AACHEN)	participant	252˙788.00

Map

Project objective

A key step in the drug development process is to predict information on safety, efficacy and mechanisms of action of a candidate molecule as early as possible in the pipeline (drug screening). To accomplish this aim, physiological and pathological pre-clinical models that closely approximate the human body are required. The limited capabilities of most of the existing pre-clinical screening tools, unable to meet the physiological relevance required to screen out failing drug candidates, reflect in the current weak performances of drug discovery: high attrition rates indeed affect the process of taking drugs from lab to market. Despite emerging new technologies exist with potential for advancing the field of in vitro modelling, their successfully implementation in the drug discovery pipeline to make it more efficient is still challenging. This is also imputable to a lack of structured dialogue between academic technology providers, market-oriented and regulatory-aware CROs, Biotechs and Pharma companies, which finally affects the research, training and development pipeline. SINERGIA aims at integrating a training network where academic and non-academic actors contribute to unravel the potential of the synergistic and rational use of four key bioengineering technologies. In particular, SINERGIA features academic leading experts of i) organs-on-chip and microfabrication technologies; ii) bioreactor and tissue engineering; iii) 3D Bioprinting; iv) induced-pluripotent human stem cells. These techniques are deployed to CROs and Biotech Consortium members that will ensure rational development, exploitation, validation and compliancy with regulatory and industrial aspects. Ultimately, this concerted action will lead to advanced models of human physiology and diseases to be introduced in preclinical stages of an innovative and improved drug discovery pipeline.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SINERGIA" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SINERGIA" are provided by the European Opendata Portal: CORDIS opendata.