BATCIC

Bacteriophage Therapy for Catheter Infection Control

Coordinatore	UNIVERSITY OF BRIGHTON    more  Organization address address: "Lewes Road, Mithras House" city: BRIGHTON postcode: BN2 4AT contact info Titolo: Dr. Nome: Brian Cognome: Jones Email: send email Telefono: +44 1273 642098
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	1˙078˙314 €
EC contributo	1˙078˙314 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2011-IAPP
Funding Scheme	MC-IAPP
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-02-01   -   2016-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY OF BRIGHTON  Organization address address: "Lewes Road, Mithras House" city: BRIGHTON postcode: BN2 4AT contact info Titolo: Dr. Nome: Brian Cognome: Jones Email: send email Telefono: +44 1273 642098	UK (BRIGHTON)	coordinator	371˙007.00
2	UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK  Organization address address: Western Road city: CORK postcode: - contact info Titolo: Dr. Nome: David Cognome: O'connell Email: send email Telefono: +353 21 490 3501 Fax: +353 21 490 3506	IE (CORK)	participant	388˙826.00
3	BIOCONTROL LIMITED  Organization address address: GEORGE STREET 79 city: ISLE OF WIGHT postcode: PO33 2JF contact info Titolo: Prof. Nome: Mark Cognome: Enright Email: send email Telefono: +44 845 680 0971	UK (ISLE OF WIGHT)	participant	195˙525.00
4	TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY  Organization address address: Oak Park city: CARLOW contact info Titolo: Ms. Nome: Mary Cognome: O'brien Email: send email Telefono: +353 45 42320 Fax: +353 25 42320	IE (CARLOW)	participant	122˙956.00

Mappa

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 Obiettivo del progetto (Objective)

'The primary aim of this project is to develop novel bacteriophage based strategies to combat Proteus mirabilis catheter associated urinary tract infection (CAUTI), a prevalent health-care associated infection for which there are currently no effective countermeasures. Indwelling urethral catheters (IUC) are the most commonly deployed medical devices, it is estimated that ~100 million IUC are used annually in healthcare systems globally, which equates to ~190 catheterisations per minute. However, IUC are vulnerable to infection, undermining their utility, jeopardising patient welfare and posing a substantial economic burden on healthcare systems. Over 40% of CAUTIs may be attributed to P. mirabilis, which poses particular problems in the care of catheterised patients. P. mirabilis causes encrustation and blockage of catheters, leading to serious complications such as pyelonephritis, septicaemia and shock. It is difficult to eliminate from the catheterised urinary tract, even after the catheter is removed, and often causes chronic infection recalcitrant to conventional antibiotic therapy. Given the prolific use of IUC and corresponding prevalence of CAUTIs in healthcare systems across the world, development of bacteriophage based strategies for control of CAUTIs would open a niche in a global market that is projected to reach an annual value of €2 billion by 2015.'