EURHEALTHAGEING

"European ResearcH on DevElopmentAL, BirtH and Genetic Determinants of Ageing"

Coordinatore	KING'S COLLEGE LONDON    more  Organization address address: Strand city: LONDON postcode: WC2R 2LS contact info Titolo: Mr. Nome: Paul Cognome: Labbett Email: send email Telefono: 442078000000 Fax: 442078000000
Nazionalità Coordinatore	United Kingdom [UK]
Sito del progetto	http://eurhealth.org/
Totale costo	3˙981˙817 €
EC contributo	2˙998˙306 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2011-two-stage
Funding Scheme	CP-FP
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-02-01   -   2015-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	KING'S COLLEGE LONDON  Organization address address: Strand city: LONDON postcode: WC2R 2LS contact info Titolo: Mr. Nome: Paul Cognome: Labbett Email: send email Telefono: 442078000000 Fax: 442078000000	UK (LONDON)	coordinator	997˙627.50
2	OULUN YLIOPISTO  Organization address address: Pentti Kaiteran Katu 1 city: OULU postcode: 90014 contact info Titolo: Mr. Nome: Arto Cognome: Eljander Email: send email Telefono: +358 8 5534133 Fax: +358 8 5534170	FI (OULU)	participant	346˙320.00
3	AIT Austrian Institute of Technology GmbH  Organization address address: Donau-City-Strasse 1 city: WIEN postcode: 1220 contact info Titolo: Mr. Nome: Felix Cognome: Schröpfer Email: send email Telefono: +43 5 0550 2069 Fax: +43 5 0550 2097	AT (WIEN)	participant	326˙806.00
4	UNIVERSITY OF SOUTHAMPTON  Organization address address: Highfield city: SOUTHAMPTON postcode: SO17 1BJ contact info Titolo: Prof. Nome: Cyrus Cognome: Cooper Email: send email Telefono: +44 23 8076 4032 Fax: +44 23 8070 4021	UK (SOUTHAMPTON)	participant	323˙977.50
5	NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S  Organization address address: Herlev Hovedgade 207 city: Helev postcode: 2730 contact info Titolo: Dr. Nome: Thomas Cognome: Nielsen Email: send email Telefono: 4544525210	DK (Helev)	participant	322˙902.00
6	TATAA BIOCENTER AB  Organization address address: ODINSGATAN 28 city: GOTEBORG postcode: 411 03 contact info Titolo: Dr. Nome: Robert Cognome: Sjöback Email: send email Telefono: +46 31 7615710 Fax: +46 31 152890	SE (GOTEBORG)	participant	266˙571.00
7	INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS  Organization address address: Patission Str. 42 city: ATHINA postcode: 10682 contact info Titolo: Prof. Nome: Dimitris Cognome: Koutsouris Email: send email Telefono: 302108000000 Fax: 302108000000	EL (ATHINA)	participant	174˙400.00
8	SEIBERSDORF LABOR GMBH  Organization address address: Forschungszentrum city: Seibersdorf postcode: 2444 contact info Titolo: Mr. Nome: Felix Cognome: Schröpfer Email: send email Telefono: +43 5 0550 2069 Fax: +43 5 0550 2097	AT (Seibersdorf)	participant	140˙102.50
9	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM  Organization address address: 's Gravendijkwal 230 city: ROTTERDAM postcode: 3015CE contact info Titolo: Mrs. Nome: Maria Cognome: Jongerden Email: send email Telefono: +31 10 7034278	NL (ROTTERDAM)	participant	99˙600.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'Developmental plasticity modulated by epigenetic processes such as methylation and post-translational modifications is influenced by early life events and determines risk of age related diseases later in life We propose a multi-disciplinary approach incorporating biochemistry, genetics, epidemiology, epigenetics and bioinformatics to discover novel biomarkers of ageing and interventional pathways to reverse changes at an early stage. A consortium of 8 members including three SMEs leaders in genetics epigenetics, post-translational modifications and metabolomics will investigate plasticity in developmental changes at pre-natal, peri-natal and early life stages on ageing in three European cohorts with rich early life data and age-related health outcomes. The identical twin data which has extensive epigenetic, genetic and metabolomic data will be utilised as a “discovery” set and the other cohorts will be used for confirmation. This multi-disciplinary project will improve our understanding of the links between fetal or perinatal events and ageing process and by combining the latest technologies in genetics, epigenetics, metabolomics and post-translational modification technologies. It will allow to develop biomarkers of ageing that reflect the role of early development on ageing. Using the collective skills and experience of eight groups at the cutting edge of European genetic and ageing research this project will identify molecular biomarkers detectable in early life that can predict age-related health (or disease) outcomes and identify pathways for intervention that can be modified while changes are still reversible.'

Introduzione (Teaser)

The associated health care burden of an ageing population is immense. The need to identify early developmental factors affecting longevity is becoming increasingly urgent.