FLUOR21

"FLUOR21 : Synthesis, structure and function of fluorinated systems"

Coordinatore	UNIVERSITY OF DURHAM    more  Organization address address: STOCKTON ROAD THE PALATINE CENTRE city: DURHAM postcode: DH1 3LE contact info Titolo: Ms. Nome: Wendy Cognome: Harle Email: send email Telefono: +44 191 3344635 Fax: +44 191 3344634
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	3˙301˙293 €
EC contributo	3˙301˙293 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2013-ITN
Funding Scheme	MC-ITN
Anno di inizio	2014
Periodo (anno-mese-giorno)	2014-03-01   -   2018-02-28

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY OF DURHAM  Organization address address: STOCKTON ROAD THE PALATINE CENTRE city: DURHAM postcode: DH1 3LE contact info Titolo: Ms. Nome: Wendy Cognome: Harle Email: send email Telefono: +44 191 3344635 Fax: +44 191 3344634	UK (DURHAM)	coordinator	773˙613.28
2	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN  Organization address address: BELFIELD city: DUBLIN postcode: 4 contact info Titolo: Mr. Nome: Donal Cognome: Doolan Email: send email Telefono: +353 17161656 Fax: +353 17161216	IE (DUBLIN)	participant	610˙628.92
3	"USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I."  Organization address address: FLEMINGOVO NAM. 542/2 city: PRAHA 6 postcode: 16610 contact info Titolo: Dr. Nome: Petr Cognome: Beier Email: send email Telefono: +42 0220183409	CZ (PRAHA 6)	participant	425˙920.00
4	THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS  Organization address address: NORTH STREET 66 COLLEGE GATE city: ST ANDREWS FIFE postcode: KY16 9AJ contact info Titolo: Mrs. Nome: Trish Cognome: Starrs Email: send email Telefono: +44 1334467286 Fax: +44 1334 462217	UK (ST ANDREWS FIFE)	participant	290˙556.64
5	ALMAC SCIENCES LIMITED  Organization address address: ALMAC HOUSE - SEAGOE INDUSTRIAL ESTATE 20 city: CRAIGAVON postcode: BT63 5QD contact info Titolo: Ms. Nome: Maureen Cognome: Lennon Email: send email Telefono: +44 2838 395882	UK (CRAIGAVON)	participant	256˙152.17
6	UNIVERSITAT WIEN  Organization address address: UNIVERSITATSRING 1 city: WIEN postcode: 1010 contact info Titolo: Dr. Nome: Helmut Cognome: Schaschl Email: send email Telefono: +43 14277 18218 Fax: +43 14277818218	AT (WIEN)	participant	245˙750.56
7	FREIE UNIVERSITAET BERLIN  Organization address address: Kaiserswertherstrasse 16-18 city: BERLIN postcode: 14195 contact info Nome: Sandy Cognome: Leitner Email: send email Telefono: +49 3083850588	DE (BERLIN)	participant	233˙200.00
8	WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER  Organization address address: SCHLOSSPLATZ 2 city: MUENSTER postcode: 48149 contact info Titolo: Dr. Nome: Katharina Cognome: Steinberg Email: send email Telefono: +49 2518322151 Fax: +49 2518322348	DE (MUENSTER)	participant	233˙200.00
9	ASTRAZENECA AB  Organization address address: Vastra Maelarhamnen city: SODERTAELJE postcode: 151 85 contact info Titolo: Dr. Nome: Laurent Cognome: Knerr Email: send email Telefono: +46 317065788	SE (SODERTAELJE)	participant	232˙272.06

Mappa

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 Obiettivo del progetto (Objective)

'Organofluorine chemistry has played a significant role in the majority of the spectacular scientific and technological developments of the past century although this is not widely recognised even by the scientific community. Fluoroorganic molecules are key components in an ever increasing number of high-value commercially important products particularly in the life science industries. The use of fluorinated systems in drug discovery programmes has continued to grow and, at present, approximately 30% of new pharmaceutical and agrochemical systems that enter the market bear fluorine atoms or fluorinated substituents, contributing enormously to the economic wellbeing of the EU as a whole and the health of its citizens. All useful fluoroorganic systems are ‘man-made’ and the key step in developing new products and applications involving fluorinated derivatives is the synthesis of carbon-fluorine bonds. We will develop new selective fluorination processes by using both innovative chemoselective methodology and the emerging field of synthetic biology to provide new technology platforms beyond the current state-of-the-art. The desire to introduce a fluorine atom into an organic system is often driven by the fact that the C-F bond imparts unique and highly tuneable control of both geometric and stereoelectronic phenomena within a molecular structure. The Network’s expertise in handling and analysing fluorinated molecules will allow us to engineer the properties of organic and biological molecules through the strategic introduction of C-F bonds by molecular editing. A large number of world-leading research scientists in academia in the various fields of organofluorine chemistry have retired in the recent past and, consequently, if training of ESRs and support of youthful research groups is not continued, the EU will lose very competitive, highly valuable, high technology, research expertise that contributes significantly to all chemical, life science and materials sectors.'