AMCARE
Advanced Materials for Cardiac Regeneration (AMCARE)
| Coordinatore | ROYAL COLLEGE OF SURGEONS IN IRELAND
Organization address
address: Saint Stephen's Green 123 contact info |
| Nazionalità Coordinatore | Ireland [IE] |
| Totale costo | 8˙694˙507 € |
| EC contributo | 6˙795˙349 € |
| Programma | FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies |
| Code Call | FP7-NMP-2013-SME-7 |
| Funding Scheme | CP-TP |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-11-01 - 2017-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ROYAL COLLEGE OF SURGEONS IN IRELAND
Organization address
address: Saint Stephen's Green 123 contact info |
IE (DUBLIN) | coordinator | 1˙250˙230.00 |
| 2 |
CARDIO3 BIOSCIENCES SA
Organization address
address: RUE EDOUARD BELIN 12 contact info |
BE (MONT SAINT GUIBERT) | participant | 1˙228˙480.00 |
| 3 |
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Organization address
address: College Green - contact info |
IE (DUBLIN) | participant | 803˙806.00 |
| 4 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse 27C contact info |
DE (MUENCHEN) | participant | 733˙429.00 |
| 5 |
ADJUCOR GMBH
Organization address
address: MENZINGER STRASSE 163 contact info |
DE (MUNCHEN) | participant | 704˙480.00 |
| 6 |
EXPLORA SRL
Organization address
address: Via Giacomo Peroni 386 contact info |
IT (ROMA) | participant | 655˙700.00 |
| 7 |
CONTIPRO BIOTECH SRO
Organization address
address: DOLNI DOBROUC 401 contact info |
CZ (DOLNI DOBROUC) | participant | 456˙880.00 |
| 8 |
INNOVA SPA
Organization address
address: Via della Scrofa 117 contact info |
IT (ROMA) | participant | 375˙845.00 |
| 9 |
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Organization address
address: GESCHWISTER-SCHOLL-PLATZ contact info |
DE (TUEBINGEN) | participant | 359˙631.00 |
| 10 |
BOSTON SCIENTIFIC IRELAND LIMITED
Organization address
address: BALLYBRIT BUSINESS PARK contact info |
IE (BALLYBRIT GALWAY) | participant | 226˙868.00 |
Mappa
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Obiettivo del progetto (Objective)
'The Advanced Materials for Cardiac Regeneration (AMCARE) consortium aims to establish a translational research program to develop truly restorative therapies for acute myocardial infarction repair (MI) by optimising cardiac progenitor cell (CPC) therapy using smart biomaterials and advanced drug delivery, and coupling these therapeutics with minimally-invasive surgical devices. Two distinct biomaterial delivery systems for CPCs will be investigated in the AMCARE work programme including HA-based patches (CardioPatch) and HA-hydrogels (CardioGel). We also propose to develop two prototypes of new surgical devices [C-CathGel and SPREDS] that will ensure a minimally invasive delivery and fixation approach that is safe and effective for each therapeutic. The combinations of advanced material carriers and surgical devices will be assessed in a large animal model of acute-MI to best align our approach to clinical translation. The novel formulations and delivery methods will help post-MI patients in restoring cardiac function by targeting for repair the underlying myocardium damage, and could potentially decrease morbidity and mortality in the future. These goals will be achieved by integrating numerous areas of materials science and stem cell biology as well as leaders in the field of medical devices, biomaterials and cardiovascular regeneration. We thus aim to improve long-term healthcare of EU citizens by offering a revolutionary therapeutic modality for the treatment of acute-MI.'
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