AUTOFLOW
Automation of Flow Cytometric Analysis for Quality-Assured Follow-up Assessment to Guide Curative Therapy for Acute Lymphoblastic Leukaemia in Children
| Coordinatore | TECHNISCHE UNIVERSITAET WIEN
Organization address
address: Karlsplatz 13 contact info |
| Nazionalità Coordinatore | Austria [AT] |
| Totale costo | 1˙638˙478 € |
| EC contributo | 1˙638˙478 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2013-IAPP |
| Funding Scheme | MC-IAPP |
| Anno di inizio | 2014 |
| Periodo (anno-mese-giorno) | 2014-02-01 - 2018-01-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
TECHNISCHE UNIVERSITAET WIEN
Organization address
address: Karlsplatz 13 contact info |
AT (WIEN) | coordinator | 508˙605.25 |
| 2 |
INFOKOM Informations- und Kommunikationsgesellschaft mbH
Organization address
address: JOHANNESSTRASSE 8 contact info |
DE (NEUBRANDENBURG) | participant | 368˙404.97 |
| 3 |
LABDIA LABORDIAGNOSTIK GMBH
Organization address
address: ZIMMERMANNPLATZ 8 contact info |
AT (WIEN) | participant | 303˙369.56 |
| 4 |
CogVis Software und Consulting GmbH
Organization address
address: WIEDNER HAUPTSTRASSE 17 3 A contact info |
AT (WIEN) | participant | 266˙557.28 |
| 5 |
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Organization address
address: Chariteplatz 1 contact info |
DE (BERLIN) | participant | 191˙541.90 |
Mappa
Word cloud
Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.
Obiettivo del progetto (Objective)
'Acute Lymphoblastic Leukaemia is the most frequent leukaemia entity in children and adolescents. Despite continued progress and refinement of therapeutic approaches, disease relapse due to insufficient extinction of leukaemic blasts still remains the number one cause of treatment failure. About 15-20% of paediatric patients with the disease still suffer from relapse. Flow cytometry (FCM) is one of the methodologies most useful in this respect, because it is widely available and applicable to most patients. While sample preparation, antibody panels, staining procedures, and FCM acquisition can be harmonized straightforwardly, data analysis and interpretation rely largely on operator skills and experience. These assessments are time-consuming and costly to be attained via staff-training, online support between twinning laboratories, and continued quality control. Hence, these requirements represent the current bottleneck of safely applying the FCM-Minimal Residual Desease (MRD) methodology in a growing community of diagnostic laboratories to the benefit of an increasing number of patients with leukaemia. To address this bottleneck, AutoFLOW aims at developing an objective and automated tool for multi-parameter FCM data analysis with robust and reliable MRD quantification. The consortium aims at engaging professionals from the medical and ICT fields in a network where the exchange of knowledge will culminate in a valid solution for automated FCM analysis for clinical follow-up assessment of Acute Lymphoblastic Leukaemia (ALL). Additionally, AutoFLOW is expected to gain better career perspectives for the involved personnel and increase the competitiveness of the participating SMEs.'