NANOSCALE
Understanding interactions between cells and nanopatterned surfaces
| Coordinatore | SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI
Organization address
address: VIA BONOMEA 265 contact info |
| Nazionalità Coordinatore | Italy [IT] |
| Sito del progetto | http://www.nanoscale-fp7.eu/ |
| Totale costo | 3˙960˙781 € |
| EC contributo | 3˙030˙405 € |
| Programma | FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies |
| Code Call | FP7-NMP-2007-SMALL-1 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-07-01 - 2011-06-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI
Organization address
address: VIA BONOMEA 265 contact info |
IT (TRIESTE) | coordinator | 0.00 |
| 2 |
CONSIGLIO NAZIONALE DELLE RICERCHE
Organization address
address: Piazzale Aldo Moro 7 contact info |
IT (ROMA) | participant | 0.00 |
| 3 |
DANMARKS TEKNISKE UNIVERSITET
Organization address
address: Anker Engelundsvej 1, Building 101A contact info |
DK (KONGENS LYNGBY) | participant | 0.00 |
| 4 |
ECOLE NORMALE SUPERIEURE
Organization address
address: "45, RUE D'ULM" contact info |
FR (PARIS CEDEX 05) | participant | 0.00 |
| 5 |
Glance Vision Technologies s.r.l.
Organization address
address: VIA GIOVANNI SEGANTINI 1/1 contact info |
IT (Trieste) | participant | 0.00 |
| 6 |
MULTI CHANNEL SYSTEMS MCS GMBH
Organization address
address: ASPENHAUSTRASSE 21 contact info |
DE (REUTLINGEN) | participant | 0.00 |
| 7 |
NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN
Organization address
address: Markwiesenstrasse 55 contact info |
DE (REUTLINGEN) | participant | 0.00 |
| 8 |
Promoscience srl
Organization address
address: LOCALITA PADRICIANO 99 contact info |
IT (TRIESTE) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'The study of biological processes occurring at the nanoscale is becoming a new discipline at the border between Physics and Biology with major scientific challenges and new technological applications. In fact, interactions at the nanoscale between cells/neurons and surfaces with specific nanopatterns appear to control several major biological processes, such as cell proliferation and differentiation. The aim of the present NanoScale proposal is therefore to explore interactions between stem cells, neurons, neuronal networks and surfaces with specific geometrical nanopatterns and nanoprints of specific proteins and molecules. In order to do so, we have formed an interdisciplinary consortium consisting of five major European research centres (SISSA, TASC-INFM, DTU, NMI and ENS) with two SMEs (MCS, Promoscience) gathering biological knowledge and expertise in the fabrication of nanostructures and of their manipulation. The NanoScale proposal will produce and develop a variety of nanodevices for growing, guiding, manipulating cells, neurons and neuronal cultures. It is composed of two major ingredients: i - the combination of a MicroElectrode Arrays (MEAs) with chemical and topographic micro/nanosubstrates controlling the network growth; ii – the coupling with external measuring and/or manipulating devices such as Electron Microscopes and Optical Tweezers. We expect to provide an answer to new scientific issues and therefore achieving major scientific breakthroughs. In addition, our proposal will produce new knowledge and know-how enabling the development of new marketable products that will be commercialised by MCS.'
Introduzione (Teaser)
Understanding neuronal signalling is essential for treating neurodegenerative diseases. The goal of the NANOSCALE project was to explore interactions between stem cells, neurons, neuronal networks and surfaces with microelectrode arrays attached to the in vitro cultivated neurons.