MSOT

Next Generation in-vivo imaging platform for post-genome biology and medicine

Coordinatore	TECHNISCHE UNIVERSITAET MUENCHEN    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Germany [DE]
Totale costo	1˙999˙992 €
EC contributo	1˙999˙992 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2008-AdG
Funding Scheme	ERC-AG
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-03-01   -   2014-06-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH  Organization address address: Ingolstaedter Landstrasse 1 city: MUENCHEN postcode: 85764 contact info Titolo: Dr. Nome: Juergen Cognome: Ertel Email: send email Telefono: +49 89 3187 3022 Fax: +49 89 3187 3866	DE (MUENCHEN)	beneficiary	92˙253.97
2	TECHNISCHE UNIVERSITAET MUENCHEN  Organization address address: Arcisstrasse 21 city: MUENCHEN postcode: 80333 contact info Titolo: Ms. Nome: Ulrike Cognome: Ronchetti Email: send email Telefono: -28922656 Fax: -28922660	DE (MUENCHEN)	hostInstitution	1˙907˙738.00
3	TECHNISCHE UNIVERSITAET MUENCHEN  Organization address address: Arcisstrasse 21 city: MUENCHEN postcode: 80333 contact info Titolo: Prof. Nome: Vasilis Cognome: Ntziachristos Email: send email Telefono: +49 89 31873852 Fax: +49 89 3187 3008	DE (MUENCHEN)	hostInstitution	1˙907˙738.00

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 Obiettivo del progetto (Objective)

'With re-defined challenges in post-genome biology and medicine related to understanding the regulation and function of genes, proteins and multi-factorial disease, the development of accelerated and quantitative in-vivo observation of functional -omics at different system levels becomes a vital target. This proposal offers to develop therefore a next-generation biomedical imaging platform, designed to radically impact biomedical and drug discovery applications. The imaging strategy aims at resolving powerful optical reporters (fluorescent proteins, nanoparticles, optical probes) with 10-100 micron resolution and femptomole sensitivity through several millimeters to centimeters of tissue. This performance brings unprecedented ability to non-invasively visualize biological and molecular processes in-vivo in intact organisms over time.

To achieve these goals, the proposal considers first the development of multi-spectral opto-acoustic tomography (MSOT) as a high performance method for revolutionizing biomedical imaging. Then, the proposal offers to develop powerful application areas in visualizing functional –omics, disease growth and drug effectiveness. The advancements offered herein can become a highly preferred biomedical imaging modality while offering ground-breaking imaging performance, safe non-ionizing radiation, an easy to disseminate platform, and unparalleled flexibility in capitalizing on powerful optical contrast using molecular reporters.'