BIOMONAR
Biosensor nanoarrays for environmental monitoring
| Coordinatore | SYDDANSK UNIVERSITET
Organization address
address: CAMPUSVEJ 55 contact info |
| Nazionalità Coordinatore | Denmark [DK] |
| Sito del progetto | http://www.sdu.dk/Om_SDU/Institutter_centre/Ifk_fysik_og_kemi/Forskning/Forskningsgrupper/Raewyn_M_Town/BIOMONAR.aspx |
| Totale costo | 3˙912˙456 € |
| EC contributo | 2˙997˙486 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2009-3 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-04-01 - 2014-03-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
SYDDANSK UNIVERSITET
Organization address
address: CAMPUSVEJ 55 contact info |
DK (ODENSE M) | coordinator | 508˙558.00 |
| 2 |
UNIVERSITE DE LAUSANNE
Organization address
city: LAUSANNE contact info |
CH (LAUSANNE) | participant | 471˙561.00 |
| 3 |
WAGENINGEN UNIVERSITY
Organization address
address: DROEVENDAALSESTEEG 4 contact info |
NL (WAGENINGEN) | participant | 462˙954.00 |
| 4 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | participant | 393˙078.00 |
| 5 |
THE HEBREW UNIVERSITY OF JERUSALEM.
Organization address
address: GIVAT RAM CAMPUS contact info |
IL (JERUSALEM) | participant | 343˙759.00 |
| 6 |
JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION
Organization address
address: Rue de la Loi 200 contact info |
BE (BRUSSELS) | participant | 278˙556.00 |
| 7 |
LIONIX BV
Organization address
address: HENGELOSESTRAAT 500 contact info |
NL (ENSCHEDE) | participant | 235˙491.00 |
| 8 |
CORNELL UNIVERSITY CORPORATION
Organization address
address: PINE TREE ROAD 373 contact info |
US (ITHACA NY) | participant | 156˙779.00 |
| 9 |
MICRODISH BV
Organization address
address: HAZENAKKER 18 contact info |
NL (HOUTEN) | participant | 106˙750.00 |
| 10 |
APPLIKON ANALYTICAL
Organization address
address: De Brauwweg 13 contact info |
NL (Schiedam) | participant | 40˙000.00 |
Mappa
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Obiettivo del progetto (Objective)
'BIOMONAR develops multiplexed nanoarray biosensors for environmental targets, i.e. pollutants and pathogens. The innovative approach engineers three sensor platforms (surface, liposomal, living cell) which exploit a panel of periplasmic binding proteins (PBPs) as the common selective element. The nanoarrays are integrated into a microfluidics system for in-situ monitoring. The strategy allows for selective and sensitive detection of target compounds in complex environmental mixtures. The sensor platforms probe different aspects in the ‘exposure to effect’ chain of processes: each responds to a certain proportion of the total target concentration and has a characteristic dynamic window. The sensor signals are quantitatively interpreted and represented in terms of the spectra of reactivities and fluxes of the target compounds. This level of sophistication, coupled with the common PBP selective component, allows a coherent elucidation of the link between dynamic target speciation and predicted ecotoxicological impact. The optimisation and dedication of the sensors for environmental monitoring inherently involves physicochemical characterisation of the various bio/nonbio and bio/bio interfacial processes at nanoscale. The ensuing knowledge on the interaction of nanostructured surfaces with biological systems facilitates design of sensors for new targets, thus providing technical opportunities for the biosensor industry.'
Introduzione (Teaser)
New-generation biosensors adapted for a range of different targets are set to raise the standard of environmental monitoring.