SUPROGAL

SUstainable PROduction of GALanthamine by both in vitro and agricultural crops of highly galanthamine-containing plants

 Coordinatore  

 Organization address address: GRAN VIA DE LES CORTS CATALANES 585
city: BARCELONA
postcode: 8007

contact info
Titolo: Prof.
Nome: Carles
Cognome: Codina
Email: send email
Telefono: 34934024493
Fax: 34934029043

 Nazionalità Coordinatore Non specificata
 Sito del progetto http://www.suprogal.eu/
 Totale costo 1˙343˙680 €
 EC contributo 787˙160 €
 Programma FP7-SME
Specific Programme "Capacities": Research for the benefit of SMEs
 Code Call FP7-SME-2007-1
 Funding Scheme BSG-S
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-02-01   -   2011-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITAT DE BARCELONA

 Organization address address: GRAN VIA DE LES CORTS CATALANES 585
city: BARCELONA
postcode: 8007

contact info
Titolo: Prof.
Nome: Carles
Cognome: Codina
Email: send email
Telefono: 34934024493
Fax: 34934029043

ES (BARCELONA) coordinator 0.00
2    VITROFLORA Laboratorium Kultur Tkankowych

 Organization address address: UL. BUKOWA 3
city: LOCHOWO
postcode: 86 065

contact info
Titolo: Mrs.
Nome: Anna
Cognome: Pawlak
Email: send email
Telefono: +48 52 3257000
Fax: +48 52 3262050

PL (LOCHOWO) participant 232˙815.00
3    BV AMARYLLIS KWEEKERIJ LUDWIG & CO

 Organization address address: MIDDENWEG 13
city: LISSE
postcode: 2161 LR

contact info
Titolo: Mr.
Nome: Rudolf
Cognome: Berbee
Email: send email
Telefono: +31 651 610320
Fax: +31 252 220428

NL (LISSE) participant 221˙980.00
4    Holland Biodiversity B.V.

 Organization address address: Middenweg 13
city: Lisse
postcode: 2161 LR

contact info
Titolo: Ms.
Nome: Diane
Cognome: Bentvelzen
Email: send email
Telefono: 31651182104
Fax: 31252220428

NL (Lisse) participant 180˙125.00
5    BULPHYTOOILS JOINTSTOCK COMPANY BPHO

 Organization address address: Tvardishki Prohod Street 23 Office 4
city: Sofia
postcode: 1404

contact info
Titolo: Mr.
Nome: Dimitar
Cognome: Shopov
Email: send email
Telefono: 35929583034
Fax: 35929583134

BG (Sofia) participant 152˙240.00
6    AGROBIOINSTITUTE

 Organization address address: Bul. Dragan Tzankov 8
city: SOFIA
postcode: 1164

contact info
Titolo: Dr.
Nome: Violeta
Cognome: Kondakova
Email: send email
Telefono: 35929635413
Fax: 35929635408

BG (SOFIA) participant 0.00
7    BIOPLANTA GmbH

 Organization address address: Deutscher Platz 5
city: Leipzig
postcode: 4103

contact info
Titolo: Dr.
Nome: Dirk
Cognome: Wilken
Email: send email
Telefono: 493412000000
Fax: 493412000000

DE (Leipzig) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

vitro    crops    narcissus    galanthamine    initiation    plant    populations    natural    plants    galanthus    species       aestivum    leucojum    smes    confusus    mainly   

 Obiettivo del progetto (Objective)

'Galanthamine is an alkaloid produced exclusively by plants of the family Amaryllidaceae, mainly belonging to the genus Galanthus, Leucojum and Narcissus. Owing to its acetylcholinesterase inhibitory activity, galanthamine is used and marketed for the treatment of the Alzheimer’s disease, among others. Although it is obtained by organic synthesis, galanthamine is also being extracted from natural sources. Both Galanthus and Leucojum plants are very widespread in the Eastern European countries, whereas Narcissus plants are mainly distributed in the Mediterranean region. For industrial purposes, Leucojum aestivum plants are gathered from wild populations in their natural habitat, which causes increasing problems regarding quality of the plant material as well as depletion pressure on the natural populations of L. aestivum. By development of an in vitro production method, both problems will be overcome. Narcissus confusus, an endemic species growing in Spain, was found to produce around two-fold higher amount of galanthamine than L. aestivum. Both plant species will also be propagated and subjected to further agronomic studies for the initiation of new crops of highly galanthamine-containing plants. Integrating both research approaches, the initiation of new crops of L. aestivum and N. confusus and the establishment of the in vitro production method, will result in the development of a sustainable production method of galanthamine. Since galanthamine in Europe is produced by highly specialised SMEs, significant improvement in this field can only be achieved by cooperation on European level. The co-operative research implemented in the SUPROGAL project will thus markedly improve the competitiveness of the involved SMEs.'

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