NEXTGEN
Next generation methods to preserve farm animal biodiversity by optimizing present and future breeding options
| Coordinatore | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
| Nazionalità Coordinatore | France [FR] |
| Sito del progetto | http://nextgen.vitamib.com |
| Totale costo | 3˙758˙355 € |
| EC contributo | 2˙999˙999 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2009-3 |
| Funding Scheme | CP-FP-SICA |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-04-01 - 2014-03-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | coordinator | 1˙257˙443.00 |
| 2 |
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Organization address
address: Meyerhofstrasse 1 contact info |
DE (HEIDELBERG) | participant | 353˙104.00 |
| 3 |
CARDIFF UNIVERSITY
Organization address
address: Newport Road 30-36 contact info |
UK (CARDIFF) | participant | 253˙968.00 |
| 4 |
UNIVERSITA CATTOLICA DEL SACRO CUORE
Organization address
address: Largo Agostino Gemelli 1 contact info |
IT (MILANO) | participant | 250˙376.00 |
| 5 |
PARCO TECNOLOGICO PADANO S.R.L.
Organization address
address: Via Einstein - Localita Cascina Codazza contact info |
IT (LODI) | participant | 236˙880.00 |
| 6 |
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Organization address
address: BATIMENT CE 3316 STATION 1 contact info |
CH (LAUSANNE) | participant | 189˙504.00 |
| 7 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
Organization address
address: AVENUE DE LA VICTOIRE contact info |
MA (RABAT) | participant | 143˙808.00 |
| 8 |
UNIVERSITA DEGLI STUDI DI TERAMO
Organization address
address: VIALE CRUCIOLI 122 contact info |
IT (TERAMO) | participant | 135˙828.00 |
| 9 |
MAKERERE UNIVERSITY
Organization address
address: Main Campus contact info |
UG (KAMPALA) | participant | 109˙200.00 |
| 10 |
Gorgan University of Agricultural Science and Natural resources
Organization address
address: Shahid Beheshti street contact info |
IR (GORGAN) | participant | 69˙888.00 |
| 11 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Organization address
address: LIMESTONE AVENUE - CAMPBELL contact info |
AU (CANBERRA) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'NEXTGEN proposes the bold step of using whole genome data to develop and optimise conservation genetic management of livestock diversity for the foreseeable future. The rationale for choosing whole genome data is to ‘future-proof’ DNA-based analysis in livestock conservation against upcoming changes in technology and analysis. Thus, in the context of whole genome data availability, our global objective is to develop cost-effective optimized methodologies for preserving farm-animal biodiversity, using cattle, sheep, and goats as model species. More specifically, NEXTGEN will: - produce whole genome data in selected populations; - develop the necessary bioinformatics approaches, taking advantage of the 1000 human genomes project, and focusing on the identification of genomic regions under recent selection (adaptive / neutral variation); - develop the methods for optimizing breeding and biobanking, taking into account both neutral and adaptive variations; - develop innovative biobanking methods based on freeze-dried nuclei; - provide guidelines for studying disease resistance and genome/environment relationships in a spatial context; - assess the value of wild ancestors and breeds from domestication centres as genetic resources; - assess the performance of a surrogate marker system compared with whole genome sequence data for preserving biodiversity; - provide efficient training and a wide dissemination of the improved methodologies. The consortium has been designed to specifically reach these objectives, and encompasses skills in conservation genetics, bioinformatics, biobanking and breeding technologies, GIScience. The work plan has been established with great care. The sequencing task has been postponed to year 3 to take advantage of cost dynamics, while the two first years are dedicated to bioinformatics and to an innovative sampling strategy that fully integrates the spatial aspect and that offers more value at the data analysis stage.'