EUCOMMTOOLS

EUCOMM: Tools for Functional Annotation of the Mouse Genome

Coordinatore	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH    more  Organization address address: Ingolstaedter Landstrasse 1 city: MUENCHEN postcode: 85764 contact info Titolo: Dr. Nome: Jürgen Cognome: Ertel Email: send email Telefono: +49 89 3187 3022 Fax: +49 89 3187 3866
Nazionalità Coordinatore	Germany [DE]
Totale costo	18˙169˙877 €
EC contributo	11˙999˙673 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2010-single-stage
Funding Scheme	CP-IP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-10-01   -   2015-09-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH  Organization address address: Ingolstaedter Landstrasse 1 city: MUENCHEN postcode: 85764 contact info Titolo: Dr. Nome: Jürgen Cognome: Ertel Email: send email Telefono: +49 89 3187 3022 Fax: +49 89 3187 3866	DE (MUENCHEN)	coordinator	4˙717˙398.55
2	GENOME RESEARCH LIMITED  Organization address address: THE GIBBS BUILDING, EUSTON ROAD 215 city: LONDON postcode: NW1 2BE contact info Titolo: Dr. Nome: Derek Cognome: Matthews Email: send email Telefono: +44 1223 492331 Fax: +44 1223 496802	UK (LONDON)	participant	4˙743˙667.00
3	UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE  Organization address address: AVENIDA DE LA UNIVERSIDAD S/N city: ELCHE postcode: 3202 contact info Titolo: Mr. Nome: Rafael Cognome: Gandía- Balaguer Email: send email Telefono: +34 966 658 782 Fax: +34 966 658 666	ES (ELCHE)	participant	589˙165.25
4	TECHNISCHE UNIVERSITAET DRESDEN  Organization address address: HELMHOLTZSTRASSE 10 city: DRESDEN postcode: 1069 contact info Titolo: Mr. Nome: Sven Cognome: Kreigenfeld Email: send email Telefono: +49 351 4633 9744 Fax: +49 351 4633 9742	DE (DRESDEN)	participant	568˙800.00
5	CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE  Organization address address: Rue Laurent Fries 1 city: ILLKIRCH GRAFFENSTADEN postcode: 67404 contact info Titolo: Dr. Nome: Steve Cognome: Brooks Email: send email Telefono: +33 3 88 65 33 94 Fax: +33 3 88 65 32 03	FR (ILLKIRCH GRAFFENSTADEN)	participant	360˙000.00
6	CONSIGLIO NAZIONALE DELLE RICERCHE  Organization address address: Piazzale Aldo Moro 7 city: ROMA postcode: 185 contact info Titolo: Ms. Nome: Assunta Cognome: Vesce Email: send email Telefono: +39 06 9091207 Fax: +39 06 90090261	IT (ROMA)	participant	359˙604.00
7	EUROPEAN MOLECULAR BIOLOGY LABORATORY  Organization address address: Meyerhofstrasse 1 city: HEIDELBERG postcode: 69117 contact info Titolo: Dr. Nome: Phil Cognome: Irving Email: send email Telefono: +49 6221 3878 239 Fax: +49 6221 3878 301	DE (HEIDELBERG)	participant	278˙800.93
8	MONASH UNIVERSITY  Organization address address: Wellington Road city: VICTORIA postcode: 3800 contact info Nome: Silvio Cognome: Tiziani Email: send email Telefono: +61 3 9902 9603	AU (VICTORIA)	participant	222˙199.07
9	UNIVERSIDAD DE MURCIA  Organization address address: AVENIDA TENIENTE FLOMESTA S/N - EDIFICIO CONVALECENCIA city: MURCIA postcode: 30003 contact info Titolo: Ms. Nome: Maria Cognome: Sánchez-Merenciano Juárez Email: send email Telefono: +34 86888 7625	ES (MURCIA)	participant	160˙038.20
10	MEDICAL RESEARCH COUNCIL  Organization address address: NORTH STAR AVENUE POLARIS HOUSE city: SWINDON postcode: SN2 1FL contact info Titolo: Dr. Nome: Hilary Cognome: Gates Email: send email Telefono: +44 1235 841252 Fax: +44 1235 841280	UK (SWINDON)	participant	0.00
11	THE JACKSON LABORATORY NON PROFIT CORPORATION  Organization address address: MAIN STREET 610 city: BAR HARBOR postcode: 4609 contact info Titolo: Dr. Nome: Stephen Cognome: Murray Email: send email Telefono: +1 207 288 6857	US (BAR HARBOR)	participant	0.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'The EUCOMMTOOLS Collaborative Project responds to the topic ‘HEALTH.2010.2.1.1-1: Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease.’ EUCOMMTOOLS will provide, in a systematic high-throughput way, genetic tools and resources contributing to the determination of every gene’s function in any cell type of the entire organism at any given point in time. To contribute to the IKMC goals, EUCOMMTOOLS will establish 250 BAC-CreERT2 transgenic mice allowing inducible conditional gene inactivation in most cell types of the organism at any given point in time. Furthermore, EUCOMMTOOLS will establish 3.500 additional, conditionally targeted mouse ES cells to complete the IKMC resource. In addition, various important technological developments will valorise the EUCOMMTOOLS resources: a genetic toolkit for multipurpose usage of the conditional knockout alleles, and improvements of the Cre-recombinase function. The EUCOMMTOOLS Cre transgenic resource as well as its library of conditionally mutated mouse ES cells enables the establishment of mutant mice world-wide in a standardized, cost-effective and time-saving manner, making mouse mutants more easily available to the wider biomedical research community than possible previously. All EUCOMMTOOLS vectors, mutant ES cells and mice will be displayed via the EUCOMMTOOLS web portal and will be distributed by EuMMCR and EMMA to the scientific community. In general, EUCOMMTOOLS fosters existing European consortia which address mouse functional genomics, mouse mutant phenotyping, and mouse archiving. Taken together, EUCOMMTOOLS will further advance the functional annotation of the entire mouse genome and thereby enhance the understanding of the molecular basis of disease. Furthermore, it will support drug development by SMEs and the pharmaceutical industry.'

Introduzione (Teaser)

Elucidation of gene function is central to understanding mammalian biology. An international consortium is pursuing this grand plan by developing genetic tools and resources to functionally annotate the entire mouse genome.