AMYLOMICS

AmylolEnzymes Captured by Targeted Metagenomics

Coordinatore	MATIS OHF    more  Organization address address: VINLANDSLEID 12 city: REYKJAVIK postcode: 112 contact info Titolo: Dr. Nome: Gudmundur Oli Cognome: Hreggvidsson Email: send email Telefono: +354 8585047 Fax: +354 4225003
Nazionalità Coordinatore	Iceland [IS]
Totale costo	3˙550˙541 €
EC contributo	2˙448˙158 €
Programma	FP7-KBBE Specific Programme "Cooperation": Food, Agriculture and Biotechnology
Code Call	FP7-KBBE-2010-4
Funding Scheme	CP-FP
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-03-01   -   2014-02-28

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	MATIS OHF  Organization address address: VINLANDSLEID 12 city: REYKJAVIK postcode: 112 contact info Titolo: Dr. Nome: Gudmundur Oli Cognome: Hreggvidsson Email: send email Telefono: +354 8585047 Fax: +354 4225003	IS (REYKJAVIK)	coordinator	638˙546.00
2	RIJKSUNIVERSITEIT GRONINGEN  Organization address address: Broerstraat 5 city: GRONINGEN postcode: 9712CP contact info Titolo: Mr. Nome: Jan Cognome: Poutsma Email: send email Telefono: +3150 3634142 Fax: +31 50 3634500	NL (GRONINGEN)	participant	415˙643.00
3	UNIVERSITAET STUTTGART  Organization address address: Keplerstrasse 7 city: STUTTGART postcode: 70174 contact info Titolo: Prof. Nome: Ralf Cognome: Mattes Email: send email Telefono: +49 711 685 66971 Fax: +49 711 685 66973	DE (STUTTGART)	participant	371˙160.00
4	LUNDS UNIVERSITET  Organization address address: Paradisgatan 5c city: LUND postcode: 22100 contact info Titolo: Prof. Nome: Olov Cognome: Sterner Email: send email Telefono: 46462224626 Fax: 46462224713	SE (LUND)	participant	370˙564.00
5	SEMGEN DOO ZA RACUNALNO PROGRAMIRANJE I SAVJETOVANJE  Organization address address: LANISTE 5D city: ZAGREB postcode: 10000 contact info Titolo: Prof. Nome: Daslav Cognome: Hranueli Email: send email Telefono: +385 1 4605013 Fax: +385 1 4836083	HR (ZAGREB)	participant	208˙351.00
6	ROQUETTE FRERES SA  Organization address address: RUE DE LA HAUTE LOGE city: LESTREM postcode: 62136 contact info Titolo: Dr. Nome: Cédric Cognome: De Coninck Email: send email Telefono: 33321635197 Fax: 33321633850	FR (LESTREM)	participant	149˙214.00
7	Ingenza Limited  Organization address address: Wallace Building, Roslin BioCentre city: Roslin postcode: EH25 9PP contact info Titolo: Dr. Nome: Ian Cognome: Fotheringham Email: send email Telefono: +44 131 200 6355 Fax: +44 131 200 6353	UK (Roslin)	participant	122˙418.00
8	PROKAZYME EHF  Organization address address: VINLANDSLEIO 14 city: REYKJAVIK postcode: 113 contact info Titolo: Dr. Nome: Jakob Cognome: Krisjánsson Email: send email Telefono: +354 664 7908 Fax: +354 664 7908	IS (REYKJAVIK)	participant	110˙902.00
9	ROCHE NIMBLEGEN INC  Organization address address: SOUTH ROSA ROAD 504 city: MADISON WI postcode: 53719 contact info Titolo: Dr. Nome: Sigridur Cognome: Valgeirsdottir Email: send email Telefono: 3544142100 Fax: 3544142109	US (MADISON WI)	participant	61˙360.00

Mappa

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 Obiettivo del progetto (Objective)

'The aim of the AMYLOMICS project is to develop novel, robust enzymes for the starch and carbohydrate industries. The novel enzymes should enable the formation of new primary products, such as oligosaccharides of defined sizes, composition and degree of branching, new types of linkages, cyclic or more complex polysaccharides and an increased digestive resistance, as well as secondary sugar derivatives such as substituted starches, rare sugars or novel isomers.

Fundamental to the success of the project will be the development of an efficient metagenomic platform technology for enzyme screening based on massive parallel 454 sequencing and microarray sequence capture. This platform will enable “genome walking” of complex metagenomic DNA and greatly facilitate the access to the largely unexplored wealth of genes in the environment.

The starch industry is the most developed sector of the polysaccharide industry and European companies play a leading role in the world market. The industry is in a constant need for a range of robust enzymes that can be used for the synthesis, fractionation and/or modification of carbohydrates. It actively searches for sustainable and more economical alternatives to existing techniques, both for the production of novel higher value products and for the improvement of older processes. The metagenomic mining platform developed in the project is expected to provide a large number of robust thermophilic starch and carbohydrate modifying enzymes and lead to new and improved biocatalytic process technologies. Lead users of the project’s results will be companies like the project partners Roquette Frères, a world leader in starch processing, Roche Molecular Systems, a leading providers of new tools, technologies and services in the genomic industry, and SME companies like Prokazyme who through the improvement of sequence based metagenomic bioprospecting platform can expand their product range of speciality products.'