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PRINT-AID SIGNED

Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

PRINT-AID project word cloud

Explore the words cloud of the PRINT-AID project. It provides you a very rough idea of what is the project "PRINT-AID" about.

tools agent platform approval microbial infective taught opens printed resist 85 network expertise structured biofilm performed biofilms alteration demonstrated education economic surfaces purpose etn innovative guide receive infections academic ec possibilities people vitro 80 sales 37 prevent dramatic drug medical sectoral print annual strategy doctoral received inhibition polymers discovery integration report marginal according 12 anti routes tissue printing deaths surface antimicrobials counteract models half intersectoral inspire aid technologies eur carrier combined surrounding 500k 3d million material science highlighted billion smes 25k implants employing don driving standardization reg companies catheters personalized young earlier fabricating exploration sterilex online bacterial inter device quality training healthcare data antibiotics medicine first courses vivo incorporated antimicrobial date ecdc industrial regulatory

Project "PRINT-AID" data sheet

The following table provides information about the project.

Coordinator	HELSINGIN YLIOPISTO Organization address address: YLIOPISTONKATU 3 city: HELSINGIN YLIOPISTO postcode: 14 website: www.helsinki.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Finland [FI]
Project website	http://printaid-etn.eu/
Total cost	2˙265˙900 €
EC max contribution	2˙265˙900 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2016
Funding Scheme	MSCA-ITN-ETN
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	HELSINGIN YLIOPISTO HELSINGIN YLIOPISTO Organization address address: YLIOPISTONKATU 3 city: HELSINGIN YLIOPISTO postcode: 14 website: www.helsinki.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (HELSINGIN YLIOPISTO)	coordinator	538˙290.00
2	APTUIT (VERONA) SRL APTUIT (VERONA) SRL Organization address address: VIA ALESSANDRO FLEMING 4 city: VERONA postcode: 37135 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (VERONA)	participant	258˙061.00
3	AMC MEDICAL RESEARCH BV AMC MEDICAL RESEARCH BV Organization address address: MEIBERGDREEF 9 city: AMSTERDAM ZUIDOOST postcode: 1105AZ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM ZUIDOOST)	participant	255˙374.00
4	UNIVERSITEIT ANTWERPEN UNIVERSITEIT ANTWERPEN Organization address address: PRINSSTRAAT 13 city: ANTWERPEN postcode: 2000 website: www.ua.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (ANTWERPEN)	participant	250˙560.00
5	UNIVERSITEIT GENT UNIVERSITEIT GENT Organization address address: SINT PIETERSNIEUWSTRAAT 25 city: GENT postcode: 9000 website: http://www.ugent.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (GENT)	participant	250˙560.00
6	VOXDALE BVBA VOXDALE BVBA Organization address address: BIJKHOEVELAAN 32C city: WIJNEGEM postcode: 2110 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (WIJNEGEM)	participant	250˙560.00
7	UNIVERSIDADE DO PORTO UNIVERSIDADE DO PORTO Organization address address: PRACA GOMES TEIXEIRA city: PORTO postcode: 4099 002 website: http://www.up.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (PORTO)	participant	238˙356.00
8	POLITECHNIKA WARSZAWSKA POLITECHNIKA WARSZAWSKA Organization address address: PLAC POLITECHNIKI 1 city: WARSZAWA postcode: 00 661 website: http://www.pw.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (WARSZAWA)	participant	224˙137.00
9	Academisch Medisch Centrum bij de Universiteit van Amsterdam Academisch Medisch Centrum bij de Universiteit van Amsterdam Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	0.00
10	3DTECH OY 3DTECH OY Organization address address: HYVONINKATU 1 city: SALO postcode: 24240 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (SALO)	partner	0.00
11	BioSurface Technologies Corporation BioSurface Technologies Corporation Organization address address: "421 West Griffin Drive #2" city: Bozeman postcode: 59715 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (Bozeman)	partner	0.00
12	MADAM THERAPEUTICS BV MADAM THERAPEUTICS BV Organization address address: KADE 1 city: ZEVENHOVE postcode: 2435 NM website: www.madam-therapeutics.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ZEVENHOVE)	partner	0.00
13	Montana State University Bozeman Montana State University Bozeman Organization address address: Montana Hall 309 city: Bozeman postcode: 59717 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (Bozeman)	partner	0.00

Map

Project objective

According to ECDC, over 4 million healthcare-associated infections in the EU cause 37,000 deaths and cost EUR 7 billion/year. Half of them are related to medical devices (i.e., catheters, implants) and 80% of these are related to bacterial biofilms. A recent EC report highlighted the medical device sector’s role in driving EU economic growth, employing 500k people in 25k companies (80% are SMEs) with annual sales of EUR 85 billion. The strategy to prevent medical device-infections is alteration of the device’s surface with antimicrobials. However, current antimicrobial surfaces don’t control bacterial growth in tissue surrounding implants, and only Sterilex® has received regulatory approval in the US as anti-biofilm agent. Participants in this proposal have earlier demonstrated a dramatic in vitro inhibition of biofilm formation by 3D-printing surfaces with antibiotics incorporated into the carrier polymers. This discovery opens new possibilities for printed medical devices that better resist biofilms. Our objective is to set-up a new European education platform to guide and inspire young researchers in the intersectoral exploration of innovative routes to counteract microbial biofilms by fabricating anti-infective, tailored, 3D-printed medical devices. Current opportunities for young researchers to receive an structured, inter-sectoral and up-to-date education on personalized medicine and medical devices are marginal, and to our knowledge PRINT-AID is the first ETN set up for this purpose. State-of-the-art printing technologies will be combined with in vitro and in vivo biofilm models and novel tools for data integration/standardization. Doctoral training will be performed within a high-quality network of 12 participants (5 industrial) from the EU and US. It will include online and face-to-face courses taught by researchers with academic and industrial expertise in biofilms, 3D-printing research, antimicrobials, material science, and drug development.

Deliverables

List of deliverables.
Methodological pipeline	Other	2020-02-19 17:56:59
A manual of standardized methods and minimum information guidelines for biofilm experiments	Documents, reports	2020-02-19 17:56:59
ESR recruitment course for ESR selection	Other	2020-02-19 17:56:57
PRINT-AID website and social media	Websites, patent fillings, videos etc.	2020-02-19 17:56:57

Take a look to the deliverables list in detail: detailed list of PRINT-AID deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Shella Gilbert-Girard, Malena Skogman, Kirsi Savijoki, Jari Yli-Kauhaluoma and Adyary Fallarero Optimization of a high-throughput screening platform in 384 well plates for exploration of anti-biofilm activity based on resazurin and crystal violet staining published pages: , ISSN: , DOI:	Abstracts, poster, Biofilms 8 Conference	2020-02-19
2018	Frits van Charante, Charlotte Courtens, Serge van Calenbergh, Tom Coenye The effect of fosmidomycin prodrugs against Acinetobacter baumannii and Burkholderia cenocepacia published pages: , ISSN: , DOI:	Abstract, poster, BSM Conference	2020-02-19
2018	Augusto Vazquez, Livia Ferrari, Antonio Felici In-vivo evaluation of biofilm inhibitor-based formulations on printed femur implants published pages: , ISSN: , DOI:	Poster, PhD Day at the Life and Health Sciences School University of Verona	2020-02-19
2018	C.M. Guarch PÃ©rez, M. Riool and S.A.J.Zaat Development of personalized anti-infective medical devices in EU training consortiumÂ PRINT-AID published pages: , ISSN: , DOI:	Abstract/poster, KNVM&NVMM Dutch Conference	2020-02-19
2018	David MartÃnez PÃ©rez1, Clara Guarch PÃ©rez2, Nehar Ã‡elikkin1, Emilia ChoiÅ„ska1, Sebastian Zaat2, Wojciech ÅšwiÄ™szkowski1* \"\"\"Development of dual antibiotic-loaded PLGA microparticles - GelMAhydrogel formulations for 3D Printing technologies\"\"\" published pages: , ISSN: , DOI:	Abstract, poster, International Conference on Biofabrication 2018	2020-02-19
2017	Juliana ??+ published pages: , ISSN: , DOI:		2020-02-19
2018	Jontana Allkja, Darla M. Goeres, Nuno Filipe Azevedo Development of minimum information guidelines and standardized microtiter plate methods for biofilm experiments published pages: , ISSN: , DOI:	Abstract, poster, Montana Biofilm Science and Technology Meeting	2020-02-19
2018	C.M. Guarch PÃ©rez, M. Riool and S.A.J.Zaat Development of personalized anti-infective medical devices in EU training consortiumÂ PRINT-AID published pages: , ISSN: , DOI:	Abstract, poster, 29th ESB Biomaterials Congress	2020-02-19
2018	David MartÃnez PÃ©rez1, Clara Guarch PÃ©rez2, Nehar Ã‡elikkin1, Emilia ChoiÅ„ska1, Sebastian Zaat2, Wojciech ÅšwiÄ™szkowski1* \"\"\"Development of PLGA microparticles - GelMAhydrogel formulations with antimicrobialproperties for 3D Printing technologies\"\"\" published pages: , ISSN: , DOI:	Abstract, poster, European Society of Biomaterials (ESB) 2018	2020-02-19
2018	C.M. Guarch PÃ©rez, M. Riool and S.A.J.Zaat In vivo mouse evaluation of 3D printed femur biomaterials published pages: , ISSN: , DOI:	Poster, PhD retreat Amsterdam Infection & Immunity Institute	2020-02-19
2018	Juliana Aizawa Porto de Abreu ESR fellow PRINT AID project published pages: , ISSN: , DOI:	Oral presentation, Recruitment event Integrated Training on Dry Eye Disease Drug Development IT-DED	2020-02-19
2018	C.M. Guarch Perez 3D printed formulations to prevent biomaterial bone infections published pages: , ISSN: , DOI:	Oral presentation, DIAGNOSTISCHE UND THERAPEUTISCHE MATERIALIEN ZUR BEKÃ„MPFUNG BAKTERIELLER INFEKTIONEN, International Summer School	2020-02-19
2018	InÃ©s Reigada, Ilkka Miettinen, Kirsi Savijoki, Adyary Fallarero Orthogonal Approaches for Studying Bacterial Biofilms using Photometric Detection with Thermo Scientific Multiskan Sky and Brightfield Imaging with EVOS FL Auto Imaging System published pages: , ISSN: , DOI:	Application note, Thermo Fisher Scientific	2020-02-19
2018	Cristina Moliner; InÃ©s Reigada; Carlota GÃ³mez-RincÃ³n; Malena Skogman; Adyary Fallarero Effects of African marigold (Tagete erecta) on Staphylococcus aureus (ATCC25923), Staphylococcus aureus Newman and Staphylococcus epidermis (ATCC RP62A) biofilms published pages: , ISSN: , DOI:	Abstract, poster, Biofilms 8 Conference	2020-02-19

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The information about "PRINT-AID" are provided by the European Opendata Portal: CORDIS opendata.

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