ANTIGONE
ANTIcipating the Global Onset of Novel Epidemics
| Coordinatore | ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Organization address
address: 's Gravendijkwal 230 contact info |
| Nazionalità Coordinatore | Netherlands [NL] |
| Totale costo | 15˙686˙261 € |
| EC contributo | 11˙997˙709 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2011-two-stage |
| Funding Scheme | CP-IP |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-11-01 - 2016-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Organization address
address: 's Gravendijkwal 230 contact info |
NL (ROTTERDAM) | coordinator | 1˙550˙500.00 |
| 2 |
UNIVERSIDAD DE CASTILLA - LA MANCHA
Organization address
address: CALLE ALTAGRACIA 50 contact info |
ES (CIUDAD REAL) | participant | 1˙541˙501.00 |
| 3 |
THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS
Organization address
address: Area 1A, Nobel House, Smith Square 17 contact info |
UK (LONDON) | participant | 1˙273˙718.00 |
| 4 |
FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT
Organization address
city: GREIFSWALD-INSEL RIEMS contact info |
DE (GREIFSWALD-INSEL RIEMS) | participant | 1˙160˙010.00 |
| 5 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Organization address
address: 101 Rue de Tolbiac contact info |
FR (PARIS) | participant | 1˙000˙000.00 |
| 6 |
Academisch Medisch Centrum bij de Universiteit van Amsterdam
Organization address
address: MEIBERGDREEF 9 contact info |
NL (AMSTERDAM) | participant | 904˙500.00 |
| 7 |
UNIVERSITAETSKLINIKUM BONN
Organization address
address: Sigmund-Freud-Strasse 25 contact info |
DE (BONN) | participant | 901˙000.00 |
| 8 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
UK (CAMBRIDGE) | participant | 864˙500.00 |
| 9 |
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
Organization address
address: SCHLOSSPLATZ 2 contact info |
DE (MUENSTER) | participant | 750˙880.00 |
| 10 |
INSTITUT PASTEUR
Organization address
address: RUE DU DOCTEUR ROUX 25-28 contact info |
FR (PARIS CEDEX 15) | participant | 624˙000.00 |
| 11 |
"Zoological Society of London, Institute of Zoology"
Organization address
address: Regent's Park contact info |
UK (London) | participant | 573˙100.00 |
| 12 |
"Biologicke centrum AV CR, v. v. i."
Organization address
address: Branisovska 31 contact info |
CZ (CESKE BUDEJOVICE) | participant | 490˙000.00 |
| 13 |
ARISTOTELIO PANEPISTIMIO THESSALONIKIS
Organization address
address: Administration Building, University Campus contact info |
EL (THESSALONIKI) | participant | 320˙000.00 |
| 14 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | participant | 44˙000.00 |
Mappa
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Obiettivo del progetto (Objective)
'In recent years, an increased number of zoonotic viruses and bacteria have crossed the species barrier to humans and caused or threatened to cause human pandemics with high morbidity and mortality. Because of our inability to predict the emergence of these pathogens, it is difficult to take preventive measures. It is known that zoonotic pathogens need to cross barriers at the animal-human interface, at the pathogen-host interface within humans, and at the human-human interface before they can cause a human pandemic. However, it is poorly understood which pathogen, host, arthropod vector, and environmental factors allow zoonotic pathogens to successfully cross these barriers. Therefore, our overall objective is to identify the key factors that render zoonotic pathogens prone to cross the species barrier and gain efficient transmissibility among humans. ANTIGONE has a two-pronged approach to reach this objective. First, we will perform primary research studies to fill important gaps in our understanding of how zoonotic pathogens can gain pandemic potential. These studies will focus on selected viruses and bacteria, including SARS coronavirus, , Crimean-Congo haemorrhagic fever virus, Nipah virus, Ebola virus, E. coli, M. bovis, B. burgdorferi, C. burnetii and S. suis. Integral to these activities will be a cross-disciplinary training programme for young scientists (Young ANTIGONE) and a web-based pathogen information sharing platform. Second, we will organize Dahlem studies where experts from the human and veterinary fields, from within and outside ANTIGONE, will discuss key issues in infectivity, pathogenicity, and transmissibility of zoonotic pathogens and determine general criteria to assess the risk of these pathogens to gain human pandemic potential. Together, the results of these activities will improve our ability to model and predict potential human pandemics of zoonotic origin and to develop effective and timely preventive measures.'
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