BLADDER CANCER EPID

Nutrition and Bladder Cancer

 Coordinatore UNIVERSITEIT MAASTRICHT 

 Organization address address: Minderbroedersberg 4-6
city: MAASTRICHT
postcode: 6200 MD

contact info
Titolo: Mr.
Nome: Sef
Cognome: Janssen
Email: send email
Telefono: 31433881961
Fax: 31433670286

 Nazionalità Coordinatore Netherlands [NL]
 Totale costo 100˙000 €
 EC contributo 100˙000 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2013-CIG
 Funding Scheme MC-CIG
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-09-01   -   2017-08-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITEIT MAASTRICHT

 Organization address address: Minderbroedersberg 4-6
city: MAASTRICHT
postcode: 6200 MD

contact info
Titolo: Mr.
Nome: Sef
Cognome: Janssen
Email: send email
Telefono: 31433881961
Fax: 31433670286

NL (MAASTRICHT) coordinator 100˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

patterns    data    recommendations    risk    diet    food    cohort    play    individual    world    bladder    nutrients    dietary    concluded    carcinogenesis    cancer   

 Obiettivo del progetto (Objective)

'During the last decade I have built a research line on bladder cancer epidemiology with a specific emphasis on diet. This has led to 54/150 publications on this topic. Although, the literature is sparse, my team and others have concluded that some micronutrients in the diet such as vitamins C, E and selenium may play a preventive role in bladder carcinogenesis. We are currently pursuing this lead with two chemoprevention clinical trials, two case-control and one cohort study. Although other food products have been researched, so far the results remain inconclusive.

Our 2008 expert report for the World Health Organization concluded that the accumulated evidence on the association between specific foods, nutrients, dietary patterns and the risk of bladder cancer is still weak. This is surprising as diet is expected to play an important role in carcinogenesis because the bladder is an excretion organ. The most likely reason for this is that most previous studies have had insufficient sample size and thus lacked adequate statistical power for analyses on 1) individual food items instead of the more common but less detailed food groups, 2) for subgroup analyses and 3) for food-food interactions.

The proposed research brings together the world’s data on diet and bladder cancer. In a unique collaboration, researchers from 26 case-control studies and 15 cohort studies across the world have agreed to share their nutritional data with over 30.000 participants including over 10.000 bladder cancer patients.

The project aims to provide definite answers on which individual food products, nutrients, existing diets (both regionally and culturally defined) and adherence dietary recommendations could influence bladder cancer risk. In addition, contemporary principle components and machine-learning algorithms will be used to identify novel explanatory dietary patterns. The results will be used to update existing dietary recommendations for the prevention of bladder cancer.'

Altri progetti dello stesso programma (FP7-PEOPLE)

CRAG (2013)

"A coupled ice sheet - ocean model for calibrated prediction of the future contribution to sea level change from the Pine Island Glacier, Antarctica"

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CYTODEV (2013)

Functions of the midbody ring in embryogenesis and tumorigenesis

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MEDEPIMIR (2011)

Novel si/miRNAs in epigenetic regulation of salt stress responses in M. truncatula

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