Phast-ID

Robust, affordable photonic crystal sensors for point-of-care disease diagnostics

Coordinatore	UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK    more  Organization address address: Lee Maltings, Prospect Row city: Cork postcode: N/A contact info Titolo: Mr. Nome: Conor Cognome: Delaney Email: send email Telefono: +353 21 4904263 Fax: +353 21 4904058
Nazionalità Coordinatore	Ireland [IE]
Totale costo	3˙548˙414 €
EC contributo	2˙680˙000 €
Programma	FP7-ICT Specific Programme "Cooperation": Information and communication technologies
Code Call	FP7-ICT-2009-5
Funding Scheme	CP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-09-01   -   2014-03-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK  Organization address address: Lee Maltings, Prospect Row city: Cork postcode: N/A contact info Titolo: Mr. Nome: Conor Cognome: Delaney Email: send email Telefono: +353 21 4904263 Fax: +353 21 4904058	IE (Cork)	coordinator	0.00
2	LUNDS UNIVERSITET  Organization address address: Paradisgatan city: LUND postcode: 22100 contact info Titolo: Ms. Nome: Marianne Cognome: Olsson Email: send email Telefono: +46 46 2224320 Fax: +46 46 2224200	SE (LUND)	participant	0.00
3	SIERRA SENSORS GMBH  Organization address address: FALKENRIED city: HAMBURG postcode: 20251 contact info Titolo: Mr. Nome: Christopher Cognome: Whalen Email: send email Telefono: +49 40 46069654 Fax: +49 40 46069746	DE (HAMBURG)	participant	0.00
4	TEKNOLOGIAN TUTKIMUSKESKUS VTT  Organization address address: TEKNIIKANTIE city: ESPOO postcode: 02044 VTT contact info Titolo: Ms. Nome: Eija Cognome: Hyvonen Email: send email Telefono: +358 20722 2404 Fax: +358 20 722 2320	FI (ESPOO)	participant	0.00
5	THE UNIVERSITY OF MANCHESTER  Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL contact info Titolo: Ms. Nome: Liz Cognome: Fay Email: send email Telefono: 441613000000 Fax: 441613000000	UK (MANCHESTER)	participant	0.00
6	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN  Organization address address: Belfield Campus city: DUBLIN postcode: 4 contact info Titolo: Mr. Nome: Donal Cognome: Doolan Email: send email Telefono: +353 01 7161 656 Fax: +353 01 7161216	IE (DUBLIN)	participant	0.00

Mappa

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 Obiettivo del progetto (Objective)

Point-of-care testing is essential to provide better patient care by aiding physicians in making informed decision during patient visits. This will enable the start of immediate treatment for many conditions and reduce the strain on resources in secondary care, resulting in reduced outpatient clinic time. A key challenge in the development of point-of-care diagnostic devices is the requirement for robust, rapid and simple assay formats with direct readout, coupled with small sensing areas (~10 x 10 µm) and low sample volumes (25 µl) that exhibit the same sensitivity as laboratory based tests. The RAPID project will address this challenge by developing an integrated multichannel 2D photonic crystal based disposable biosensor and bench top reader, for point-of-care disease diagnostic applications. The RAPID disposable sensor will demonstrate enhanced performance beyond the state of the art in key proteomic diagnostic systems by delivering direct robust label-free detection of four pancreatic cancer serum biomarkers at less than 100 fM (5 pg/ml) concentrations. Objective genetic algorithms will be developed for infometric and chemometric pattern recognition to allow unequivocal identification of protein cancer biomarkers following collection of the data from the sensor platform. In this manner, the project will support the development of future device innovation in proteomics and disease diagnostics that could yield revolutionary advances in healthcare and nanomedicine. A successful RAPID project will provide a number of clear benefits over the current label-free commercial offerings: speed, cost and ease of use and make the outputs of the RAPID project very attractive commercially in the PoC diagnostic markets.