The page lists 74 projects related to the topic "dysregulation".
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1 | CoordinatedDopamine | Coordination of regional dopamine release in the striatum during habit formation and compulsive behaviour | 2015 |
2 | SCORA | A systematic characterization of human regulatory architectures and their determinants of regulatory activity | 2015 |
3 | MetaFlex | Metabolic flexibility: breaking down food effectively to prolong life | 2015 |
4 | STRESSAGED | Molecular Mechanisms Linking Psychological Stress and Ageing-Related Disease | 2015 |
5 | EPIGENHEART | Epigenetic control of retinoic acid-dependent genes during heart development | 2015 |
6 | UPR NEURO | The Unfolded Protein Response in Neurodegeneration | 2015 |
7 | TransCTNeurodev | Transgenerational transmission of maternal childhood trauma and its sequelae – Altered maternal physiology during pregnancy and implications for newborn neurodevelopment | 2015 |
8 | SEPCELL | Title of Proposal: Restoring the immune system homeostasis and organ function in severe community acquired pneumonia- induced sepsis through adipose derived allogeneic stem cells (SEPCELL Proje | 2015 |
9 | THYRAGE | Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities | 2016 |
10 | OptoNMDA | Optical strategies to investigate NMDA receptor functional diversity and its therapeutic potential | 2016 |
11 | LIPID IMMUNITY | Regulation of lipid-mediated immunity in the intestine | 2016 |
12 | ERcontext | How to deal with how you feel: Understanding and training context-dependent emotion regulation | 2016 |
13 | ROQ-WACh | Identification and Characterization of Cis-Regulatory ModuleDysfunction in Rett Syndrome with ROQ-WACh | 2016 |
14 | TransGen RNA | Transgenerational regulation of glucose metabolism by noncoding RNAs | 2016 |
15 | Niche Fibrosis | Identification of regulatory signals from vascular niche in alveolar regeneration and pulmonary fibrosis | 2016 |
16 | TRANSREGULON | Structural biology of mammalian transcription regulation | 2016 |
17 | MARS | Mechanism of allosteric regulation of SHP2 phosphatase and its role in cancer and geneticdiseases: a multidisciplinary computational, structural and biological approach | 2017 |
18 | TRAIN | Tribbles Research and Innovation Network | 2016 |
19 | AlzDiabetes | Insulin resistance and Tauopathy : Insights from Drosophila models and human brain samples | 2016 |
20 | MILEAGE | Microelements in Life Expectancy and Aging | 2017 |
21 | GENE FOR CURE | Expanding and extending gene therapy of monogenic diseases of the haematopoietic system | 2016 |
22 | MIRA | Characterizing Microbe-specific Immune Responses in the pathogenesis of Autoimmunity | 2017 |
23 | EpiMethFly | Study of the role of m6A RNA methylation in the nervous system of Drosophila melanogaster: an in-vivo model to dissect the impact of epitranscriptome reprogramming in physiology and cancer | 2017 |
24 | RTKPalm | Modulating and Profiling Receptor Tyrosine Kinase S-palmitoylation in Breast Cancer | 2017 |
25 | EASY | Epigenetic approach for the treatment of obesity | 2017 |
26 | MARS | Can histone code-like switches govern the multifunctionality of RNA-binding proteins? | 2017 |
27 | InflammaTENSION | A study of the roles of the immune and inflammatory systems in hypertension. | 2017 |
28 | EpiFAT | Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes | 2017 |
29 | MECHADIAN | Mechanobiology of the cellular circadian clock | 2018 |
30 | PRIMATE-TE-IMPACT | Mapping the retrotransposon-mediated layer of neuronal gene regulation in the human genome | 2017 |
31 | GlymphEye | The Ocular Glymphatic System | 2017 |
32 | CURE | Constructing a ‘Eubiosis Reinstatement Therapy’ for Asthma | 2017 |
33 | noRAG-TOR | Rag-independent regulation of mTOR by Amino Acids | 2018 |
34 | VitASTEM | Regulation of Single Hematopoietic Stem Cells by Intake of Vitamin A | 2018 |
35 | MASTFAST | Rapid production of HUMAN MAST CELLS | 2017 |
36 | SI | Structural and functional characterization of the ICOS/ICOSL immune complex | 2018 |
37 | inhibitAUTO | Towards a New Frontier in Autophagy Inhibition: The Development of a Novel Class of ChemicalProbes and Identification of Their Associated Biological Target | 2018 |
38 | REMIX | Effects of rewiring microexons (REMIX) on tissue-specific signaling networks | 2018 |
39 | cureCD | Function of long non-coding RNA in Crohn Disease Ulcer Pathogenesis | 2018 |
40 | UB-RASDisease | The ubiquitin system in RAS-driven disease | 2018 |
41 | ANTILEAK | Development of antagonists of vascular leakage | 2018 |
42 | ImmunAID | Immunome project consortium for AutoInflammatory Disorders | 2018 |
43 | PFC-AMY | Functional networks underlying emotion processing | 2018 |
44 | iNtoPoreAge | Assessing transcriptional and nuclear pore aging in age-equivalent and rejuvenated induced neurons from Alzheimer patients | 2019 |
45 | ZELDA | Investigating the mechanism of spatiotemporal control over genome activation by Zelda in an in vitro reconstituted system | 2019 |
46 | STARTlight | STARTlight: cell cycle START decision unraveled by single-cell microscopy, modeling and optogenetics | 2018 |
47 | SKin SCiENCE | Skin Keratinocyte Stem CEll proliferatioN in field CancErisation | 2018 |
48 | ProMeta | Non-histone protein acetylation targets of KAT2A in AML | 2018 |
49 | mTORmorS | Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma | 2019 |
50 | BIOCARD | Deep BIOmodeling of human CARDiogenesis | 2018 |
51 | Myel-IN-Crisis | Myelin at the crossroads of Development and Disease | 2018 |
52 | LIGHTPORT | From light-stimulated anion receptors to transmembrane carriers and pumps | 2019 |
53 | VeCare | Selective retention of VEGF for cancer and retinopathies therapeutics | 2019 |
54 | DDRMac | DNA Damage Response-instructed Macrophage Differentiation in Granulomatous Diseases | 2019 |
55 | inCITe | Seeing Citrulline: A Molecular Toolbox for Peptidyl Arginine Deiminases | 2019 |
56 | IMMCEPTION | Nociception and sensory nerves as regulators of type 2 immunity and skin inflammation | 2019 |
57 | METAPTPs | PROTEIN TYROSINE PHOSPHATASES IN METABOLIC DISEASES: OXIDATION, DYSFUNCTION AND THERAPEUTIC POTENTIAL | 2019 |
58 | iDysChart | Charting key molecules and mechanisms of human immune Dysregulation | 2019 |
59 | INTENDeD | INTegration of EmotioNs During Decision-Making | 2020 |
60 | UreaCa | Deciphering the metabolic roles of the urea-cycle pathway in carcinogenesis for improving diagnosis and therapy | 2019 |
61 | TargetDUBs | Targeting ubiquitin processing in cancer and fibrosis: novel probes for the Ubiquitin Carboxy-Terminal Hydrolases | 2019 |
62 | DEAP | Development of Epithelium Apical Polarity: Does the mechanical cell-cell adhesions play a role? | 2019 |
63 | LIV-AD-ON-CHIP | Unmasking insulin resistance triggering mechanisms using microphysiological two-organ systems as in vitro disease models of metabolic syndrome and non-alcoholic fatty liver disease | 2020 |
64 | CLOCK | Characterization of the circadian chromatin landscape using a novel CRISPR/Cas9-guided proximity-labelling technique | 2020 |
65 | TOPAS | Exploiting the Tumor Proteome Activity Status for Future Cancer Therapies | 2019 |
66 | SA-VOIR | Assessing the feasibility of MT-011, a first-in-class drug to treat glaucoma and other neurodegenerative diseases via a breakthrough mechanism-of-action | 2019 |
67 | CANDY | Comorbid Analysis of Neurodevelopmental Disorders and Epilepsy | 2020 |
68 | TO_AITION | A high-dimensional approach for unwinding immune-metabolic causes of cardiovascular disease-depression multimorbidities | 2020 |
69 | BARRIER BREAK | Breaking the barrier: How inflammation spreads from skin to joint | 2020 |
70 | M6AQuantKit | Development and commercialization of kit for quantitative interrogation of a key RNA modification | 2020 |
71 | SILENT | Silent mutations in cancer | 2020 |
72 | CTS-TEs-ADprogress | Cell type-specific molecular analysis of epigenetic changes and transposable element derepression in Alzheimer's disease progression | 2020 |
73 | ParkIFNAR | Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context. | 2020 |
74 | TGF-BTB | Transforming Growth Factor – Bench To Bedside. Towards a better understanding of TGF-β isoform specific signalling in health and disease | 2020 |