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EVOluTION SIGNED

European Vascular Interventions and Therapeutic Innovation Network

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

EVOluTION project word cloud

Explore the words cloud of the EVOluTION project. It provides you a very rough idea of what is the project "EVOluTION" about.

vascular chemistry societal pioneering maker companies computational specialized triangle resolution training structure academic protective educational boosting angles ageing strategies interdisciplinary scientists natural sme science dietary scientific visits processes trade questions platform pharma societies pharmacology conducive medical body mechanisms business provides boost protection nutraceuticals integrating formed aligned vasculature focussed evolution local expertise network entrepreneurship patent diseases biotech exploited cross population knowledge young prevention industrial guarantee education detection skills engagement tissue answer trained communication gain leaders lab countries firm metabolic therapies western therapeutic secondments chronic tools view transferable mediators innovative creation multidisciplinary valuable maximally 11 cutting yield policy endogenous

Project "EVOluTION" data sheet

The following table provides information about the project.

Coordinator	QUEEN MARY UNIVERSITY OF LONDON Organization address address: 327 MILE END ROAD city: LONDON postcode: E1 4NS website: http://www.qmul.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	https://www.qmul.ac.uk/evolution/
Total cost	2˙887˙041 €
EC max contribution	2˙887˙041 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2015
Funding Scheme	MSCA-ITN-ETN
Starting year	2016
Duration (year-month-day)	from 2016-04-01 to 2020-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	QUEEN MARY UNIVERSITY OF LONDON QUEEN MARY UNIVERSITY OF LONDON Organization address address: 327 MILE END ROAD city: LONDON postcode: E1 4NS website: http://www.qmul.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	coordinator	819˙863.00
2	UNIVERSITEIT MAASTRICHT UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD website: http://www.maastrichtuniversity.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	participant	766˙122.00
3	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 website: www.uni-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	498˙432.00
4	LIFEARC LIFEARC Organization address address: 7TH FLOOR LYNTON HOUSE 7-12 TAVISTOCK SQUARE city: LONDON postcode: WC1H 9LT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	273˙287.00
5	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Organization address address: BELFIELD city: DUBLIN postcode: 4 website: www.ucd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	265˙674.00
6	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	263˙659.00
7	Genomics England Limited Genomics England Limited Organization address address: 4TH FLOOR SKIPTON HOUSE 80 LONDON ROAD city: London postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (London)	partner	0.00
8	Kilburn & Strode Kilburn & Strode Organization address address: n.a. city: London postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (London)	partner	0.00
9	MosaMedix MosaMedix Organization address address: Oude Rijksweg Zuid 21 city: Susteren postcode: 6114 RC website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (Susteren)	partner	0.00
10	QUINTILES LIMITED QUINTILES LIMITED Organization address address: 500 BROOK DRIVE, GREEN PARK, BERKSHIRE city: READING postcode: RG2 6UU website: www.quintiles.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (READING)	partner	0.00
11	THE ROYAL SOCIETY OF CHEMISTRY THE ROYAL SOCIETY OF CHEMISTRY Organization address address: Milton Road - Thomas Graham House - Science Park city: CAMBRIDGE postcode: CB4 0WF website: www.rsc.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	partner	0.00
12	UCB PHARMA SA UCB PHARMA SA Organization address address: ALLEE DE LA RECHERCHE 60 city: BRUXELLES postcode: 1070 website: www.ucb.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	partner	0.00
13	William Harvey Research Limited William Harvey Research Limited Organization address address: n.a. city: London postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (London)	partner	0.00

Map

Project objective

EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully aligned with the knowledge triangle (business, research and higher education) platform being developed at the EU level, EVOluTION-trained young scientists will gain valuable knowledge and multidisciplinary skills: only interdisciplinary and cross-cutting research can lead to novel therapeutic tools and scientific angles to address these challenging medical, societal and industrial issues. EVOluTION provides a conducive structure by bringing 5 leading academic institutions and 1 SME, together with 6 Pharma and biotech companies, 1 Policy-maker, and 1 Patent & Trade firm as Partner Organisations, from 6 EU countries. The science of EVOluTION evolves around the innovative concept of boosting natural protective mechanisms operating in our body, focusing on the vasculature, to answer 3 key questions: Can we exploit mediators and targets of endogenous tissue protection? Can we exploit these pathways to yield innovative therapeutic strategies? Can dietary approaches boost these endogenous protective processes? The Network Partners guarantee delivery of training through knowledge creation, knowledge exploitation and knowledge communication. Scientific and educational expertise of the partners, leaders in areas like computational chemistry, nutraceuticals, resolution pharmacology and vascular therapies will be maximally exploited. The EVOluTION training platform is based on state-of-the-art lab-based and network-wide and local training activities, including secondments and scientific visits and specialized transferable skills focussed in entrepreneurship and societal engagement.

Deliverables

List of deliverables.
EVOluTION Web site	Websites, patent fillings, videos etc.	2019-07-10 10:45:12
Guidelines for recruitment strategy	Documents, reports	2019-07-10 10:45:12

Take a look to the deliverables list in detail: detailed list of EVOluTION deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Silvia Oggero, Shani Austin-Williams, Lucy Victoria Norling The Contrasting Role of Extracellular Vesicles in Vascular Inflammation and Tissue Repair published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2019.01479	Frontiers in Pharmacology 10	2020-02-19
2019	Ploingarm Petsophonsakul, Malgorzata Furmanik, Rachael Forsythe, Marc Dweck, Geert Willem Schurink, Ehsan Natour, Chris Reutelingsperger, Michael Jacobs, Barend Mees, Leon Schurgers Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation published pages: 1351-1368, ISSN: 1079-5642, DOI: 10.1161/atvbaha.119.312787	Arteriosclerosis, Thrombosis, and Vascular Biology 39/7	2020-01-29
2019	Chiara Moretti, Zhengbing Zhuge, Gensheng Zhang, Sarah McCann Haworth, Luciano L. Paulo, Drielle D. GuimarÃ£es, Josiane C. Cruz, Marcelo F. Montenegro, Isabel Cordero-Herrera, Valdir A. Braga, Eddie Weitzberg, Mattias CarlstrÃ¶m, Jon O. Lundberg The obligatory role of host microbiota in bioactivation of dietary nitrate published pages: 342-348, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.10.003	Free Radical Biology and Medicine 145	2019-10-29
2018	Monica de Gaetano, Caitriona McEvoy, Darrell Andrews, Antonino Cacace, Jonathan Hunter, Eoin Brennan, Catherine Godson Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2018.01488	Frontiers in Pharmacology 9	2019-10-15
2019	Isabel Cordero-Herrera, Mikael Kozyra, Zhengbing Zhuge, Sarah McCann Haworth, Chiara Moretti, Maria Peleli, Mayara Caldeira-Dias, Arghavan Jahandideh, Han Huirong, Josiane de Campos Cruz, Andrei L. Kleschyov, Marcelo F. Montenegro, Magnus Ingelman-Sundberg, Eddie Weitzberg, Jon O. Lundberg, Mattias Carlstrom AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis published pages: 217-226, ISSN: 0027-8424, DOI: 10.1073/pnas.1809406115	Proceedings of the National Academy of Sciences 116/1	2019-09-02
2019	Marilena Crescente, Laura Menke, Melissa V Chan, Paul C Armstrong, Timothy D Warner Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond) published pages: 988-999, ISSN: 0007-1188, DOI: 10.1111/bph.14196	British Journal of Pharmacology 176/8	2019-09-02
2019	Maurice Halder, Ploingarm Petsophonsakul, Asim Akbulut, Angelina Pavlic, Frode Bohan, Eric Anderson, Katarzyna Maresz, Rafael Kramann, Leon Schurgers Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease published pages: 896, ISSN: 1422-0067, DOI: 10.3390/ijms20040896	International Journal of Molecular Sciences 20/4	2019-09-04
2019	Bartolo Ferraro, Giovanna Leoni, Rabea Hinkel, Steffen Ormanns, Nicole Paulin, Almudena Ortega-Gomez, Joana R. Viola, Renske de Jong, Dario Bongiovanni, Tarik Bozoglu, Sanne L. Maas, Michele Dâ€™Amico, Thorsten Kessler, Tanja Zeller, Michael Hristov, Chris Reutelingsperger, Hendrik B. Sager, Yvonne DÃ¶ring, Matthias Nahrendorf, Christian Kupatt, Oliver Soehnlein Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair published pages: 2990-3002, ISSN: 0735-1097, DOI: 10.1016/j.jacc.2019.03.503	Journal of the American College of Cardiology 73/23	2019-09-02
2018	Nicole Paulin, Joana R. Viola, Sanne L. Maas, Renske de Jong, Teresa Fernandes-Alnemri, Christian Weber, Maik Drechsler, Yvonne DÃ¶ring, Oliver Soehnlein Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability published pages: 321-323, ISSN: 0009-7322, DOI: 10.1161/circulationaha.117.033098	Circulation 138/3	2019-09-02
2017	Jan Nagenborg, Pieter Goossens, Erik A.L. Biessen, Marjo M.P.C. Donners Heterogeneity of atherosclerotic plaque macrophage origin, phenotype and functions: Implications for treatment published pages: 14-24, ISSN: 0014-2999, DOI: 10.1016/j.ejphar.2017.10.005	European Journal of Pharmacology 816	2019-09-02
2017	Eoin P. Brennan, Antonino Cacace, Catherine Godson Specialized pro-resolving mediators in renal fibrosis published pages: 102-113, ISSN: 0098-2997, DOI: 10.1016/j.mam.2017.05.001	Molecular Aspects of Medicine 58	2019-09-02
2018	Joana Viola, Patricia Lemnitzer, Nicole Paulin, Maik Drechsler, Maliheh Nazari-Jahantigh, Sanne Maas, Renske De Jong, Janine Winter, Andreas Schober, Christian Weber, Kamran Atabai, Oliver Soehnlein Deletion of MFGE8 Inhibits Neointima Formation upon Arterial Damage published pages: 1340-1342, ISSN: 0340-6245, DOI: 10.1055/s-0038-1649522	Thrombosis and Haemostasis 118/07	2019-09-02
2018	Sanne L. Maas, Oliver Soehnlein, Joana R. Viola Organ-Specific Mechanisms of Transendothelial Neutrophil Migration in the Lung, Liver, Kidney, and Aorta published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.02739	Frontiers in Immunology 9	2019-09-02
2019	Monica de Gaetano, EibhlÃn Butler, Kevin Gahan, Andrea Zanetti, Mariam Marai, Jianmin Chen, Antonino Cacace, Emily Hams, Catherine Maingot, Alisha McLoughlin, Eoin Brennan, Xavier Leroy, Christine E. Loscher, Padraic Fallon, Mauro Perretti, Catherine Godson, Patrick J. Guiry Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms) published pages: 80-108, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.10.049	European Journal of Medicinal Chemistry 162	2019-07-10

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