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DRYNET SIGNED

Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking

Total Cost €

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EC-Contrib. €

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Partnership

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 DRYNET project word cloud

Explore the words cloud of the DRYNET project. It provides you a very rough idea of what is the project "DRYNET" about.

burden    economic    lay    embryogenesis    biobank    sharing    skills    generate    practices    facilities    expertise    international    drying    shipping    embryology    expressed    loaded    diagnostic    prospect    molecular    workshop    abundant    tools    biobanking    proteins    scientists    young    cryopreservation    sme    transferable    footprint    simplification    sectorial    pan    mechanical    nitrogen    guarantee    academy    natural    boosts    hazardous    smes    multidisciplinary    strengthens    public    biobanks    clinical    mathematical    pathogens    insect    japan    school    secondments    primary    block    network    biodiversity    dry    coherent    basis    career    induce    foresees    disciplines    exponentially    carbon    expensive    ensures    industry    biology    gametes    protectants    outreaching    cellular    maintenance    repository    plan    liquid    empirical    meeting    math    metabolism    summer    water    relies    cells    storage    currents    reversible    ln    preservation    merges    carries    survival    knowhow    academic    academia    inter    anhydrobiosis    xero    biophysical    thailand    though    sustainability    engineering    representing    competitiveness    drynet    nature    germplasm    purposes    strategy    theoretical    subtraction   

Project "DRYNET" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI TERAMO 

Organization address
address: VIA RENATO BALZARINI 1 3 5 7
city: TERAMO
postcode: 64100
website: www.unite.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://drynet.unite.it/
 Total cost 841˙500 €
 EC max contribution 765˙000 € (91%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2021-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TERAMO IT (TERAMO) coordinator 238˙500.00
2    BIOTALENTUM TUDASFEJLESZTO KFT HU (GOEDOELLO) participant 171˙000.00
3    UNIVERSIDAD DE BURGOS ES (BURGOS) participant 148˙500.00
4    UNIVERSITA DEGLI STUDI DI CAGLIARI IT (CAGLIARI) participant 112˙500.00
5    UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA IT (MODENA) participant 63˙000.00
6    AVANTEA srl IT (Cremona) participant 27˙000.00
7    IMAGENE FR (PESSAC) participant 4˙500.00
8    BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC) AT (GRAZ) participant 0.00
9    CHULALONGKORN UNIVERSITY TH (BANGKOK) partner 0.00
10    NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION JP (TSUKUBA IBARAKI) partner 0.00

Map

 Project objective

The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.

 Publications

year authors and title journal last update
List of publications.
2019 Debora Agata Anzalone, Luca Palazzese, Domenico Iuso, Giuseppe Martino, Pasqualino Loi
Corrigendum to “Freeze-dried spermatozoa: An alternative biobanking option for endangered species” [Anim. Reprod. Sci. 190C (2018) 85–93]
published pages: 96, ISSN: 0378-4320, DOI: 10.1016/j.anireprosci.2018.12.008
Animal Reproduction Science 202 2020-04-15
2020 Joseph Saragusty, Debora Agata Anzalone, Luca Palazzese, Amir Arav, Pasquale Patrizio, Jaime Gosálvez, Pasqualino Loi
Dry biobanking as a conservation tool in the Anthropocene
published pages: , ISSN: 0093-691X, DOI: 10.1016/j.theriogenology.2020.01.022
Theriogenology 2020-04-15
2019 Elisa Casula, Gabriele Traversari, Sarah Fadda, Oleksiy V. Klymenko, Cleo Kontoravdi, Alberto Cincotti
Modelling the osmotic behaviour of human mesenchymal stem cells
published pages: 107296, ISSN: 1369-703X, DOI: 10.1016/j.bej.2019.107296
Biochemical Engineering Journal 151 2020-04-15
2019 Marta Czernik, Debora A. Anzalone, Luca Palazzese, Mami Oikawa, Pasqualino Loi
Somatic cell nuclear transfer: failures, successes and the challenges ahead
published pages: 123-130, ISSN: 0214-6282, DOI: 10.1387/ijdb.180324mc
The International Journal of Developmental Biology 63/3-4-5 2020-04-07
2018 Takahiro G. Yamada, Yoshitaka Suetsugu, Ruslan Deviatiiarov, Oleg Gusev, Richard Cornette, Alexander Nesmelov, Noriko Hiroi, Takahiro Kikawada, Akira Funahashi
Transcriptome analysis of the anhydrobiotic cell line Pv11 infers the mechanism of desiccation tolerance and recovery
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-36124-6
Scientific Reports 8/1 2020-01-20
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-20
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-20
2018 Debora Agata Anzalone, Luca Palazzese, Domenico Iuso, Giuseppe Martino, Pasqualino Loi
Freeze-dried spermatozoa: An alternative biobanking option for endangered species
published pages: 85-93, ISSN: 0378-4320, DOI: 10.1016/j.anireprosci.2018.01.010
Animal Reproduction Science 190 2020-01-20
2018 Luca Palazzese, Marta Czernik, Domenico Iuso, Paola Toschi, Pasqualino Loi
Nuclear quiescence and histone hyper-acetylation jointly improve protamine-mediated nuclear remodeling in sheep fibroblasts
published pages: e0193954, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0193954
PLOS ONE 13/3 2020-01-20

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