The page lists 91 projects related to the topic "sclerosis".
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1 | MIROCALS | Efficacy and safety of low-dose IL-2 (ld-IL-2) as a Treg enhancer for anti-neuroinflammatory therapy in newly diagnosed Amyotrophic Lateral Sclerosis (ALS) patients | 2015 |
2 | CDS-QUAMRI | A Clinical Decision Support system based on Quantitative multimodal brain MRI for personalized treatment in neurological and psychiatric disorders | 2015 |
3 | CorticALS | Amyotrophic Lateral Sclerosis from a cortical perspective: towards alternative therapeutic strategies | 2015 |
4 | Als-on-a-chip | A tissue-on-a-chip platform for systems-level studies of ALS pathology and drug screening | 2015 |
5 | CONTESSA | COuNt data TimE SerieS Analysis: significance tests and sequencing data application | 2015 |
6 | NMJALS | In vivo analysis of neuromuscular junction stability in zebrafish models of amyotrophic lateral sclerosis | 2015 |
7 | DEALS | Biomarker assay development to expedite ALS experimental therapeutic advancement | 2015 |
8 | STEM ZAP | Optogenetics based discovery of new pathways towards stem-cell mediated myelin repair | 2016 |
9 | GAMES | Gut Microbiota in Nervous System Autoimmunity: Molecular Mechanisms of Disease Initiation and Regulation | 2015 |
10 | C9ND | C9orf72-mediated neurodegeneration: mechanisms and therapeutics | 2015 |
11 | LIFEOMEGA | Innovative highly concentrated Omega 3 food supplement | 2015 |
12 | EXODUS | Light induced spatially EXact and genetically encoded labeling of immune cells for monitoring of lOng Distance and Ultra-compartment Shuttling during autoimmunity and chronic inflammation | 2015 |
13 | BtRAIN | Brain barriers training | 2015 |
14 | IL7sigNETure | IL-7/IL-7R signaling networks in health and malignancy | 2015 |
15 | VESCEL | Vascular Engineering on chip using differentiated Stem Cells | 2015 |
16 | NISCI | Antibodies against Nogo-A to enhance plasticity, regeneration and functional recovery after acute spinal cord injury, a multicenter European clinical proof of concept trial | 2016 |
17 | PREG-LAB | Distinctive characterization of regulatory plasma cells and pro-inflammatory B cells in immunity: their origins, molecular properties, and cellular fates. | 2016 |
18 | MyeliNANO | Myelinic nanochannels in neurodegenerative diseases | 2016 |
19 | MIRASYS | The diagnostic potential of miRNAs for early diagnosis of Systemic Sclerosis | 2016 |
20 | IMPEDE | Immunomodulatory effects of sustained pantethine release in inflammatory diseases | 2016 |
21 | MS Fatigue_Therapy | Objectively Measuring MS Fatigue | 2016 |
22 | InnateMSDyn | Combining in vivo spectral biphoton imaging and multiparametric cytometry to characterize the dynamics of the innate immune response in a multiple sclerosis mouse model | 2016 |
23 | SIDSCA | Defective DNA Damage Responses in Dominant Neurodegenerative Diseases | 2016 |
24 | EPIScOPE | Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis | 2016 |
25 | OPTOGENERAPY | Optogenetic Protein Therapy for Multiple Sclerosis | 2017 |
26 | IntegraMouse3 | Next-generation, modular computer mouse device for disabled people | 2016 |
27 | FORMAT | FORMAT: a novel medium FOr Revolutionizing stem cell MAnufacturing Technologies | 2017 |
28 | MultipleMS | Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine | 2017 |
29 | NanoALS | Nanoparticle-based immunization, a novel therapeutic strategy for amyotrophic lateral sclerosis | 2018 |
30 | ExItALS | RNA-mediated intercellular miscommunication: role of extracellular vesicle cargos in Amyotrophic Lateral Sclerosis | 2017 |
31 | PhaseAge | The chemistry and physics of RNP granules: how they form, age and cause disease | 2017 |
32 | RADAR-CNS | Remote Assessment of Disease and Relapse in Central Nervous System Disorders - Sofia ref.: 115902 | 2016 |
33 | NanoZfish | Restoration of motor dysfunction in vivo through nanomaterials based devices | 2017 |
34 | CORFEDITING | Gene Editing as Therapeutic Strategy for C9ORF72 Linked ALS/FTD | 2017 |
35 | MOWOOT | Integral Intestinal Transit Management System for chronic constipation | 2017 |
36 | METAMAPPER | Super-resolution genomic mapping for the microbiome | 2017 |
37 | TOLERANCE FOOTPRINT | Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T CellRepertoire | 2017 |
38 | BrainDrain | Translational implications of the discovery of brain-draining lymphatics | 2017 |
39 | AUTOIGG | AUTOMATED FUNCTIONAL SCREENING OF IgGs FOR DIAGNOSTICS OF NEURODEGENERATIVE DISEASES | 2018 |
40 | DIDO-MS | Commercialization of a first in class multiple sclerosis drug | 2018 |
41 | TUDCA-ALS | Safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS) | 2018 |
42 | RESTORE | NEURONAL SELF-RENEWAL BY ANTIGEN-SPECIFIC TOLERIZATION IN MULTIPLE SCLEROSIS REINSTALLING THE BALANCE BETWEEN INFLAMMATION AND REGENERATION | 2018 |
43 | DeepRNA | Discovering functional protein-RNA interactions through data integration and machine learning. | 2018 |
44 | EFHHBBBMS | Endothelial Hedgehog autocrine signaling at the Blood Brain Barrier controls inflammatory CentralNervous System lesion size and severity through Gas1 co-receptor modulation. | 2019 |
45 | CRISPR-GQ | Identifying the Capabilities and Limitations of CRISPR in Targeting G-quadruplex Forming Sequences: From Target Recognition to Gene Expression Regulation | 2018 |
46 | MyelinPlasticity | Neuronal regulation of CNS myelin plasticity | 2018 |
47 | EScORIAL | Emerging Simplex ORigins In ALS | 2018 |
48 | MuSeq | Defining the Oligodendrocyte Lineage in Multiple Sclerosis Lesions by Single Cell RNA-Sequencing | 2018 |
49 | Stress Granules | Using Reconstituted Stress Granules to Gain Insight into the Molecular Pathology of Neurodegenerative Diseases | 2019 |
50 | MS-fMRI-QSM | Studying Multiple Sclerosis with a novel simultaneous functional Magnetic Resonance Imaging (fMRI) and Quantitative Susceptibility Mapping (QSM) sequence. | 2019 |
51 | Multiple Sclerosis | Development of a Functionalised Biomaterial Scaffold to Treat Multiple Sclerosis | 2018 |
52 | NeuroRBP | Studying RNA-binding proteins involved in neural differentiation and degeneration | 2019 |
53 | IMMUNEDIVERSITY | Defining of human adaptive immune gene diversity and its impact on disease | 2018 |
54 | SOLO | Single cell omics of the Oligodendrocyte Lineage in develOpment and disease | 2018 |
55 | MAPSYNE | Miniaturized automated patch-clamp system combined with high-density microelectrode arrays for multi-scale functional mapping of neuronal networks | 2018 |
56 | ASSYSt | A reliable CXCL4 biomarker assay to improve diagnosis and treatment of Systemic Sclerosis | 2018 |
57 | MOMENTS | Multi-sensory experiences for in-home therapy and entertainment | 2018 |
58 | NeuroProtect | Novel Drug Therapy with Potential to Cure Neuro-Degenerative Diseases | 2018 |
59 | Myel-IN-Crisis | Myelin at the crossroads of Development and Disease | 2018 |
60 | Combat_ALS | Development of new chemical tools to combat ALS | 2019 |
61 | MegaALS | Unravelling the Interplay between Metabolism, Gut Microbiome and Adaptive Immunity in Amyotrophic Lateral Sclerosis | 2018 |
62 | Neurovulnerability | Molecular mechanisms underlying selective neuronal death in motor neuron diseases | 2019 |
63 | FutureTrophicFactors | Elucidating therapeutic effects and mode of action of future trophic factorsin ALS and Parkinson’s disease | 2019 |
64 | Epi4MS | Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis | 2019 |
65 | ReHaptix | Easy-to-use and highly accurate medical software for quantitative assessment of impairments in neurologically injured people. | 2019 |
66 | SWALLIS | SWALLIS - a disruptive wearable device that uses sound patterns to diagnose and monitor swallowing disorders | 2019 |
67 | ReMyelin | The Cell Biology of Remyelination | 2019 |
68 | PMSMatTrain | Novel Biomaterial-based Device for the Treatment of Progressive MS- - An Integrated Pan- European Approach | 2019 |
69 | CROWDY | Toward the microscopic simulations of cell-like environments. | 2019 |
70 | LinkFM | Linking Functional impact and Microstructural properties of fiber tract demyelination and remyelination in a rodent model of multiple sclerosis | 2019 |
71 | NG2-cells | The role of NG2 cells in the neural network in health and disease | 2019 |
72 | StressOME | Defining and modulating the stress granule proteome as a therapeutic strategy in Amyotrophic Lateral Sclerosis | 2019 |
73 | MOBILISE-D | Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement | 2019 |
74 | ENTRAIN | ENdoThelial macRophage Alliance In Neuroinflammation | 2019 |
75 | Nocturne | The eye as a window to the brain, extending lifelong brain health | 2019 |
76 | Dignum | Innovative toilet assistive device enabling people with reduced mobility to become independent | 2019 |
77 | dreaMS | Digital biomarkers and treatment personalisation in multiple sclerosis | 2019 |
78 | ScleroTest | A rapid and cost-effective point-of-care diagnostic kit able to predict treatment response for appropriate Multiple Sclerosis management | 2019 |
79 | MOVEMeNt | Decoding alpha motor neurons diversity and selective vulnerability to disease | 2020 |
80 | FunStructure | Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease | 2019 |
81 | MetALS | Investigating the pharmacokinetic properties of toxic metals and heat shock proteins as risk factors in Amyotrophic Lateral Sclerosis | 2019 |
82 | IL7RsignaTHER | Antibody-based IL-7R targeted therapies | 2020 |
83 | OSAvit-D | POINT OF CARE DEVICE FOR VITAMIN D DEFICIENCY MONITORING | 2019 |
84 | NeuroPa | Targeting the brain sigma-1 receptor: A paradigm shift for the treatment of neuro-degenerative disorders | 2019 |
85 | RNPdynamics | Multivalent interactions driving RNP dynamics in development and disease | 2020 |
86 | DPR-VAX | Dipeptide-Repeat Vaccine to prevent ALS and FTD in C9orf72 mutation carriers | 2020 |
87 | MyeRIBO | Deconstructing the Translational Control of Myelination by Specialized Ribosomes | 2020 |
88 | H I C I | Transcriptional and epigenetic control of tissue regenerative HB-EGF in autoimmune CNS inflammation | 2020 |
89 | OLI.VAS | The Oligo-Vascular interface: understanding its properties and functions | 2020 |
90 | ASTRA | ASsembly and phase Transitions of Ribonucleoprotein Aggregates in neurons: from physiology to pathology. | 2020 |
91 | Ctrl-BBB | Blood-brain barrier: from molecular mechanisms to intervention strategies | 2020 |