Opendata, web and dolomites
H2020 projects about "mutation"
The page lists 132 projects related to the topic "mutation".
| # | |||
|---|---|---|---|
| 1 | PRO-CF-MED | Clinical Proof of concept for a RNA-targeting Oligonucleotide for a Cystic fibrosis-F508del MEDication | 2015 |
| 2 | GermAge | The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem | 2015 |
| 3 | MoTriColor | Molecularly guided trials with specific treatment strategies in patients with advanced newly molecular defined subtypes of colorectal cancer (MoTriColor) | 2015 |
| 4 | RevMito | Deciphering and reversing the consequences of mitochondrial DNA damage | 2015 |
| 5 | CRCStemCellDynamics | Molecular Subtype Specific Stem Cell Dynamics in Developing and Established Colorectal Cancers | 2015 |
| 6 | CULTURALBASE | Social Platform on Cultural Heritage and European Identities | 2015 |
| 7 | InVivo_DDR_ADPR | Decoding the DNA damage signalling in C. elegans by proteomic analyses of ADP-ribosylation | 2016 |
| 8 | DecipherBILU | Understanding functional mechanisms leading to the BILU syndrome | 2015 |
| 9 | CICCI | Characterization of Intestinal Cancer Cell Invasion | 2015 |
| 10 | BRIDGES | Bioinformatic approaches to identify and detect both disease- and drug-related genomic alterations in breast cancer patients | 2015 |
| 11 | IntestineUb | The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells | 2016 |
| 12 | MDR Tuberculosis | Evolution and success of the multi-drug resistant M. tuberculosis SIT41 (LAM7-TUR) lineage | 2015 |
| 13 | PopMet | Investigating bacterial strain evolution through metagenomic genome assemblies | 2015 |
| 14 | ROBUSTNET | Quantitative developmental genetic analysis of phenotypic buffering and cryptic variation | 2015 |
| 15 | TARLOOP | R-loops as a major modulator of transcription-associated recombination and chromatin dynamics | 2015 |
| 16 | TRIGGDRUG | Reactions That Translate mRNA into Drug-like Molecules | 2016 |
| 17 | DUB-DECODE | Systematic Decoding of Deubiquitylase-Regulated Signaling Networks | 2015 |
| 18 | STEMCARDIORISK | Stem Cells for Cardiac Arrhythmia Risk Assessment | 2015 |
| 19 | StemNicheOnWaveCrest | New therapies for myeloproliferative diseases based on multi-stage and -system analyses of the haematopoietic stem-cell niche | 2015 |
| 20 | RNAEDIT | RNA EDITING IN HEALTH AND DISEASE | 2016 |
| 21 | SLACC | Supplying lung adenocarcinoma cell lines to the cancer research community. | 2015 |
| 22 | CYTOPRO | Profiling of tumour cells in blood for personalized treatment of metastatic cancer | 2015 |
| 23 | PhotoMutant | Rational Design of Photoreceptor Mutants with Desired Photochemical Properties | 2016 |
| 24 | CODOVIREVOL | Evolution of viral codon usage preferences:manipulation of translation accuracy and evasion of immune response | 2016 |
| 25 | TAT-CF | Novel therapeutic approaches for the treatment of cystic fibrosis based on small molecule transmembrane anion transporters | 2016 |
| 26 | NetMoDEzyme | Network models for the computational design of proficient enzymes | 2016 |
| 27 | PreventStoCan | Understanding microbe-induced stomach cancer – the key to a workable strategy for worldwide prevention | 2016 |
| 28 | hRBP-virion | Comprehensive identification of host factors involved in the early steps of HIV infection. | 2017 |
| 29 | iGEMMdev | Development and Characterisation of New Immunogenic GEMMs of Lung Cancer | 2017 |
| 30 | ENVERESP | Crosstalk between nuclear envelope and DNA Damage Response: Role of nucleoporin TPR in the maintenance of genomic integrity | 2016 |
| 31 | CAMEOS | Cardiac micro-engineered tissue for high-throughput screening | 2016 |
| 32 | CYgnaling | Probing the role of orphan Cytochrome P450 oxygenases in signaling compounds biosynthesis in plants by a comparative genomics and gene conservation approach | 2016 |
| 33 | DesignerAntibiotics | Towards the prevention of aminoglycoside antibiotic-related deafness | 2017 |
| 34 | MITOBIOPATH | DISCOVERING NEW DISEASE PATHWAYS AFFECTING mtDNA METABOLISM | 2016 |
| 35 | EpigenomeProgramming | An experimental and bioinformatic toolbox for functional epigenomics and its application to epigenetically making and breaking a cancer cell | 2016 |
| 36 | nextDART | Next-generation Detection of Antigen Responsive T-cells | 2016 |
| 37 | DENOVOMUT | An integrated approach to understanding the impact of de novo mutations on the mammalian genome | 2017 |
| 38 | DMD2CURE | Correction of duplications in the DMD gene by a CRISPR/Cas9 approach | 2017 |
| 39 | TENSION | Targeting replication stress recovery pathways in oncology | 2016 |
| 40 | MUTX | MUTATION++ library, technology transfer from atmospheric entry plasmas to biomass pyrolysis | 2016 |
| 41 | TransSplicHD | Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. | 2016 |
| 42 | SYNTRAIN | Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network | 2016 |
| 43 | 1toStopVax | RNA virus attenuation by altering mutational robustness | 2016 |
| 44 | BRAIN REPEATS | Repeat polymorphisms as genetic modifiers of brain function in healthy subjects and Huntington disease mutation carriers | 2016 |
| 45 | URBACH-ALZ | Hyper-emotionality after neurodegenerative loss of inhibition of the amygdala | 2017 |
| 46 | LungCARD | Blood test for clinical therapy guidance of non-small cell lung cancer patients | 2017 |
| 47 | GENE FOR CURE | Expanding and extending gene therapy of monogenic diseases of the haematopoietic system | 2016 |
| 48 | IMMUNOSABR | Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer | 2017 |
| 49 | TREATCilia | Novel Therapeutic Avenues for dynein-related Ciliopathies | 2017 |
| 50 | CureTheCloves | PIK3CA inhibition in patients with the CLOVES syndrome | 2017 |
| 51 | DSR | Dissipative Self-Replication | 2017 |
| 52 | SARCOM | Selection for antimicrobial resistance in a complex community context | 2017 |
| 53 | MultiLevelLandscape | Multilevel Selection for Specificity and Divergence in Bacteria | 2017 |
| 54 | MuRChap | The mutation-buffering capacity of RNA chaperones | 2017 |
| 55 | ResistEpist | Dissection of the mechanisms causing the epistasis between antibiotic resistance mutations in Escherichia coli | 2018 |
| 56 | MuSCel Genome | Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization | 2017 |
| 57 | NeuroTRACK | Tracking and predicting neurodegeneration spreading across the brain connectome | 2017 |
| 58 | Rep. Fork Restart | Restart of blocked replication fork at replication fork barrier | 2017 |
| 59 | OPTiAGE | The trade-off between longevity and reproduction: optimal control of aging | 2018 |
| 60 | DSMT16 | Deciphering causes and consequences of inflammation in subtypes of sporadic intestinal cancer | 2018 |
| 61 | BaskAtax | Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders | 2017 |
| 62 | mtDNA-CURE | Treating mitochondrial disease caused by pathogenic mtDNA mutations | 2018 |
| 63 | BRCA-ERC | Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control | 2017 |
| 64 | V-EPC | Inherited disfunctions of brain microcirculation | 2017 |
| 65 | GermlineAgeingSoma | Getting to the root of ageing: somatic decay as a cost of germline maintenance | 2017 |
| 66 | CRISS | CRISPR Gene Correction for Severe Combined Immunodeficiency Caused by Mutations in Recombination-activating gene 1 and 2 (RAG1 and RAG2) | 2017 |
| 67 | INSITUMUT | Direct detection of cancer-causing mutations in tumour specimens | 2018 |
| 68 | EvoCellBio | A combined in vitro and in vivo approach to dissect biochemical network evolution. | 2018 |
| 69 | CLLCLONE | Harnessing clonal evolution in chronic lymphocytic leukemia | 2018 |
| 70 | ZIDOMS | Using Zebrafish as a novel tool to Improve the Diagnosis and Outcome of Marfan Syndrome | 2018 |
| 71 | EScORIAL | Emerging Simplex ORigins In ALS | 2018 |
| 72 | PSR | Photometabolic Self-Replication | 2019 |
| 73 | PrunMut | Candidate mutation discovery in early-flowering mutants 'Rojo Pasión Precoz' and 'Bulida Precoz' | 2019 |
| 74 | SunPro | Sunflower: Durable Resistance to Broomrape (Orobanche cumana Wallr.) | 2019 |
| 75 | PREMEDiCARE | PREcision MEDicine with induced pluripotent stem cells for Cardiac Arrhythmias Risk Evaluation | 2018 |
| 76 | INFLA-AID | The role of NLRC4 inflammasome in autoinflammatory diseases | 2018 |
| 77 | EvolBehavGenArch | The composition and evolution of C. elegans behavioural genetic architectures | 2018 |
| 78 | HiMIN | Histone H3.3 oncogenic mutations: a role in genome instability through altered DNA repair and replication fork stability? | 2018 |
| 79 | MiniBRAIN | Investigating the pathogenic mechanisms underlying TUBB2B-related brain malformations using induced pluripotent stem cells and cerebral organoids. | 2019 |
| 80 | ProMeta | Non-histone protein acetylation targets of KAT2A in AML | 2018 |
| 81 | GENOMIA | Genomic Modifiers of Inherited Aortapathy | 2019 |
| 82 | SILICOFCM | In Silico trials for drug tracing the effects of sarcomeric protein mutations leading to familial cardiomyopathy | 2018 |
| 83 | LEAP-EXTREME | Local Edaphic Adaptation in Plants through Leveraging an Extremophile Model | 2018 |
| 84 | cGEM | the Center for Genomics, Evolution and Medicine | 2018 |
| 85 | PITBUL | Point-of-Care implementation of TB testing with ultra-fast Local Heating PCR | 2017 |
| 86 | Fields4CAT | Force Fields in Redox Enzymatic Catalysis | 2019 |
| 87 | BioBalanced | Feasibility study for Bioapplications – BioBalanced Farm probiotic | 2018 |
| 88 | BSLchlamy | Understanding the essential function of the conserved plant-specific protein phosphatase family BSL | 2018 |
| 89 | SIGNIA | SIGNIA: An innovative drug discovery platform for rapid identification and validation of antimicrobial applications in available pharmaceutical resources and drugs open for repurposing. | 2018 |
| 90 | EVOdrops | directed EVOlution in DROPS | 2018 |
| 91 | Growth regulation | The wide-spread bacterial toxin delivery systems and their role in multicellularity | 2019 |
| 92 | Myel-IN-Crisis | Myelin at the crossroads of Development and Disease | 2018 |
| 93 | BioRoboost | Fostering Synthetic Biology standardisation through international collaboration | 2018 |
| 94 | UNIFLUVAC | A novel universal influenza vaccine targeting epitopes of limited variability | 2018 |
| 95 | StarT | European Training Network to Diagnose, Understand and Treat Stargardt Disease, a Frequent Inherited Blinding Disorder | 2018 |
| 96 | SOLID | Suppression of Organelle Defects in Human Disease | 2019 |
| 97 | HYPROTIN | Hyperpolarized Nuclear Magnetic Resonance Spectroscopy for Time-Resolved Monitoring of Interactions of Intrinsically Disordered Breast-Cancer Proteins | 2019 |
| 98 | evolSingleCellGRN | Constraint, Adaptation, and Heterogeneity: Genomic and single-cell approaches to understanding the evolution of developmental gene regulatory networks | 2019 |
| 99 | Agglomerates | Infinite Protein Self-Assembly in Health and Disease | 2019 |
| 100 | CiliaTubulinCode | Self-organization of the cilium: the role of the tubulin code | 2019 |
| 101 | ONCOFUM | Integrating the tissue-specificity and chronology of hereditary renal cancer predisposition | 2019 |
| 102 | IMaP | Imaging tumor vessels as a marker for p53 mutation status in cancer | 2020 |
| 103 | GPCR-MS | Molecular Details of Membrane Protein Receptor Dynamics | 2019 |
| 104 | SOS-CROPS | Solving the tangled ontogenesis of the stem for sustainable crops | 2019 |
| 105 | MutANTs | Mutation rate evolution in attine ants | 2020 |
| 106 | iMIND | iPS-derived MIcroglia and Neuroinflammation in Dementia | 2020 |
| 107 | 2D-MES | Two Dimensional Molecular Electronics Spectroscopy for DNA/RNA Mutation Recognition | 2020 |
| 108 | PMLingAML | Using PML nuclear body biology to identify potential AML treatment targets | 2020 |
| 109 | GenDels | Development of a new CRISPR-Cas3-based tool for large genomic deletions | 2019 |
| 110 | MalusEdit | Malus genome editing via CRISPR/Cas9 to develop sustainable pest free apples | 2019 |
| 111 | MechanoMVP | Mechanosensing and Mitral Valve Prolapse: from the Molecular Mechanisms to the Progression of the Disease | 2019 |
| 112 | IBL-302 | Inflection Bioscience unique dual mechanism, small molecule, orally available therapeutic targeting major unmet medical needs in breast cancer | 2019 |
| 113 | Genetic Vaccine | Study the therapeutic and preventive potential of targeting oncogenic mutations with CRISPR-Cas9 technology | 2019 |
| 114 | SPELITEC | Sequence sPecific ELImination of shiga-Toxin E. Coli | 2019 |
| 115 | RASMAC | Regulatory Approved Software for Mutation Analysis in Cancer | 2019 |
| 116 | FUELING-TRANSPORT | Deciphering the Role of Huntingtin in Energy Supply for Axonal Transport in Health and Huntington’s Disease | 2020 |
| 117 | MOLEC ANTI-ARRHYT | Resilience and Trigger Factors in Cardiac Arrhythmia: Risk Stratification and Drug Design | 2020 |
| 118 | GEMS | Genetically Evolving Models of Science | 2019 |
| 119 | RhabdoEvo | Deciphering the cellular origin and evolution of malignant rhabdoid tumors | 2019 |
| 120 | BIND | Brain Involvement iN Dystrophinopathies | 2020 |
| 121 | DPR-VAX | Dipeptide-Repeat Vaccine to prevent ALS and FTD in C9orf72 mutation carriers | 2020 |
| 122 | PROMISE | PROgrammable MIxed Signal Electronics | 2020 |
| 123 | RNAVirFitness | The dark side of evolution: the deleterious mutational landscape of RNA viruses | 2020 |
| 124 | ROMB | Retina Organoid Mechanobiology | 2020 |
| 125 | EvolInfome | The sources of historical signal in the genomes of birds | 2021 |
| 126 | DIFFER | Determinants of genetic diversity: Important Factors For Ecosystem Resilience | 2020 |
| 127 | ParkIFNAR | Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context. | 2020 |
| 128 | MITafterVIT | Unravelling maintenance mechanisms of immune tolerance after termination of venom immunotherapy by means of clonal mast cell diseases | 2020 |
| 129 | NOSCAR | decipheriNg Oncogenic SIgnalling patterns to break CAncer drug Resistance | 2020 |
| 130 | HiPhy | High Phytosterol variants towards improved feedstocks and biofortification of crops | 2020 |
| 131 | SecondCANCERinKIDS | What causes therapy-related malignancies in childhood cancer survivors? Dissecting the etiology of second cancers | 2020 |
| 132 | ObeSIK3 | Role of SIK3 in energy homeostasis | 2021 |