The page lists 135 projects related to the topic "mrna".
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1 | CNIDARIAMICRORNA | Elucidation of the evolution of post-transcriptional regulation by characterizing the cnidarian microRNA pathway | 2015 |
2 | BREATHE | Biochemically modified messenger RNA encoding nucleases for in vivo gene correction of severe inherited lung diseases | 2015 |
3 | LYMPHORG | Organ-specific mechanisms of lymphatic vascular development and specialisation | 2015 |
4 | MICEXPRESS | Understanding how selection for body weight in mouse operates at the RNA level | 2015 |
5 | lincPeptEvolDev | LincRNA and encoded small peptides: Functional discovery in development and evolution | 2015 |
6 | TRYP-QS | YAK kinase regulated trypanosome quorum sensing | 2015 |
7 | LARP4MOT | Structural and functional studies of LARP4, a new RNA binding protein involved in mRNA stabilisation and cell migration | 2016 |
8 | Syncrip_2014 | The molecular basis of learning and memory: uncovering the link between neuronal activation and localized translation at the synapse. | 2015 |
9 | HRPCDMECH | Investigating how pathogen effector recognition by the host plant activates cell death | 2016 |
10 | PERFECTION | Probing mechanisms of pathogen effector recognition by plant Resistance proteins to elevate defence gene activation | 2016 |
11 | MoTOR | Analysis of the “moonlighting” proteins in the mTOR-signalling pathway | 2016 |
12 | RAPID-KDM | Application of peptide screening technology for identification of substrates of the Jumonji-C histone demethylases | 2015 |
13 | SpliceosomeStructure | Structural role of protein splicing factors in promoting an active configuration of the spliceosome's RNA catalytic core | 2016 |
14 | NeuroUTR | Systematic investigation of the functional coupling between transcriptional and post-transcriptional regulatory interactions underlying tissue-specific 3'UTRs variability. | 2015 |
15 | DYS_FUNCTION | Novel use of exon skipping technology to study structure-function relationship of dystrophin | 2016 |
16 | RISH | Imaging of multiple mRNA targets using SERS nanoparticle labels and in situ hybridization in human cancer tissue sections | 2015 |
17 | RNA Transport and Control | Mechanisms of kinesin-dependent RNA transport and translational regulation | 2015 |
18 | OLIGOBINPRO | Non-canonical nucleoside incorporation into synthetic RNA-oligonucleotides: investigations towards the discovery of selective RNA-binding proteins | 2015 |
19 | CICCI | Characterization of Intestinal Cancer Cell Invasion | 2015 |
20 | REALISM | Reducing Early Atrophy with Leucine during Immobilization of Skeletal Muscle | 2015 |
21 | Beta-splicenet | ALTERNATIVE SPLICING NETWORKS IN PANCREATIC BETA CELLS | 2015 |
22 | APOBEC | Enzymatic DNA deamination and the immunity/cancer balance | 2015 |
23 | MoDATS | Model-based Data Analysis of Transcription and Splicing | 2016 |
24 | CARDIOTOX | Predicting Cardiotoxicity Induced by Kinase Inhibitors: From Systems Biology to Systems Pharmacology | 2015 |
25 | MtbTransReg | Translational regulation in the persistence and drug susceptibility of Mycobacterium tuberculosis | 2015 |
26 | BrightSens | Ultrabright Turn-on Fluorescent Organic Nanoparticles for Amplified Molecular Sensing in Living Cells | 2015 |
27 | ReguloBac-3UTR | High-throughput in vivo studies on posttranscriptional regulatory mechanisms mediated by bacterial 3'-UTRs | 2015 |
28 | INTRASTEM | INTRASTEM: High Efficiency Delivery of Proteins, Nucleic Acids and Particles to Human Cells | 2015 |
29 | DevoTed_miR | MicroRNA determinants of the balance between effector and regulatory T cells in vivo | 2015 |
30 | D-FENS | Dicer-Dependent Defense in Mammals | 2015 |
31 | Troy Stem Cells | Troy+ stomach stem cells in homeostasis, repair and pathogenesis | 2015 |
32 | TRIGGDRUG | Reactions That Translate mRNA into Drug-like Molecules | 2016 |
33 | PlasmoSilencing | Exoribonuclease-mediated degradation of nascent RNA in Malaria Parasites: A Novel Mechanism in Virulence Gene Silencing | 2015 |
34 | BacCellEpi | Bacterial, cellular and epigenetic factors that control enteropathogenicity | 2015 |
35 | CellViewer | CellViewer: super-resolution systems microscopy to assess pluripotency and differentiation of stem cells at single cell level | 2016 |
36 | DynaMech | Linking Transcription Factor Binding Dynamics to Promoter Output | 2016 |
37 | RNAREG | Single molecule observation and manipulation of gene expression dynamics to dissect mechanisms of cell cycle entry | 2016 |
38 | GvHDCure | Understanding the dynamics of the immune system to cure graft-versus-host disease (GvHD). | 2016 |
39 | ReachingCompleteness | The Molecular Basis of Somatic Nuclear Reprogramming | 2016 |
40 | TranslationRegCode | Cracking the Translation Regulatory Code | 2016 |
41 | RiboDisc | Discovery of novel orphan riboswitch ligands | 2016 |
42 | TissueMaps | Integrating spatial and genetic information via automated image analysis and interactive visualization of tissue data | 2016 |
43 | M6Abolic-RNA-duplex | Metabolic control of RNA-protein and RNA-RNA interactions in cellular transformation. | 2016 |
44 | reSGulating | Functional analysis of Stress Granules formation in plant adaptation to stress | 2017 |
45 | G4-PTROs | Regulatory network of G-quadruplex dependent Post-Transcriptional mRNA Operons (PTROs) | 2016 |
46 | Cells-in-drops | High throughput screening of single-cells using droplet microfluidics | 2016 |
47 | Prionomics | Systematic profiling of molecular changes during prion disease progression | 2016 |
48 | NanoPokers | Deciphering cell heterogeneity in tumors using arrays of nanowires to controllably poke single cells in longitudinal studies | 2016 |
49 | SPLICE3D | CryoEM studies of the spliceosome | 2016 |
50 | TRANSREGULON | Structural biology of mammalian transcription regulation | 2016 |
51 | TRANSDAM | The transcription-related DNA damage response | 2016 |
52 | dsRNAEnvFate | Environmental fate of double stranded RNA (dsRNA) from RNA interference crop protection technology in agricultural systems: A systematic assessment of dsRNA hydrolysis, adsorption, and photolysis | 2016 |
53 | GlioDx | GlioDx - Blood platelet-based monitoring and treatment optimisation for glioblastoma patients | 2016 |
54 | B-response | Memory and innate-like B-cell subsets: deciphering a multi-layered B-cell response in mice and humans | 2016 |
55 | SYNC_DEV | The importance of transcriptional coordination during development | 2017 |
56 | CrackEpitranscriptom | Cracking the epitranscriptome | 2016 |
57 | mR-NIPD | Proof of Concept study for ERC NIPD discovered biomarkers | 2016 |
58 | EVALVE | Biomechanics and signaling in models of congenital heart valve defects | 2016 |
59 | ComplexAssembly | The birth of protein complexes | 2018 |
60 | eWAD | Unbalanced Wnt signalling in AD: a DNA methylation effect | 2017 |
61 | POLYAMACHINES | The polyA machinery: Elucidating the molecular mechanisms of mRNA polyadenylation, deadenylation and RNA recognition | 2017 |
62 | SpliceCore | Functional dissection of core spliceosomal mutations causing Retinitis Pigmentosa. | 2017 |
63 | meltRBP | Tracking interactions between RNA and RNA-binding proteins by thermal profiling of the proteome | 2017 |
64 | BENDER | BiogENesis and Degradation of Endoplasmic Reticulum proteins | 2017 |
65 | DevoSignGammaDelta | Tracking γδ T cell development and TCRγδ proximal signalling | 2018 |
66 | NascenTomiX | Ribosome inhibition by nascent or antimicrobial peptides | 2017 |
67 | RNAatHD | Development of a high-resolution method to monitor structural changes of regulatory RNAs and therapeutic oligo-nucleotides directly in-cell. | 2017 |
68 | EXO-EYE | Stem Cell-Derived Exosomes for the treatment of Traumatic and Degenerative Eye Disease | 2017 |
69 | Brain_stability | Elucidating novel post-transcriptional regulatory mechanisms in neural development | 2017 |
70 | NEURO_NMD | Functional impact of alternative splicing coupled to nonsense-mediated decay in developing neurons | 2017 |
71 | IMMUNO-RQC | Role of Listerin ubiquitin ligase in MHC-I antigen presentation | 2017 |
72 | MARS | Can histone code-like switches govern the multifunctionality of RNA-binding proteins? | 2017 |
73 | IAV-m6A | Elucidating the role of m6A RNA methylation on the replication and pathogenesis of influenza A virus. | 2017 |
74 | NucLoc | RNA localization in bacteria | 2018 |
75 | PATHORISC | Reprogramming of small RNA function in plant-pathogen interactions | 2017 |
76 | dCas9 | Dissection of the mammalian transcription termination mechanism by CRISPRi technology. | 2017 |
77 | CellTrack | Cellular Position Tracking Using DNA Origami Barcodes | 2017 |
78 | EXORICO | Exosome and ribosome coupling | 2017 |
79 | m1ARNA | Transcriptomic m1A - a new key player in the epitranscriptome arena | 2017 |
80 | Epiherigans | Writing, reading and managing stress with H3K9me | 2017 |
81 | ImmortaSTEM | ImmortaSTEM: Transient Immortalisation for Patient Stem Cell Expansion and Therapeutic Application | 2017 |
82 | NeuroRibo | Specialized Ribosomes for Neuronal Protein Synthesis | 2017 |
83 | TransFold | Molecular Biology of Nascent Chains: Co-translational folding and assembly of proteins in eukaryotes | 2017 |
84 | BioProbe-PIT | Local molecular profiling of tumor tissue sections: towards personalized immunotherapy | 2017 |
85 | CYCLODE | Cyclical and Linear Timing Modes in Development | 2017 |
86 | CodeSphere | CodeSphere - Discovering Therapeutic Nanoparticles by Molecular Encoding | 2017 |
87 | SC-EpiCode | Decoding the Epigenomic Regulatory Code by the Use of Single Cell Technologies | 2017 |
88 | ESEMT | DETERMINING THE FUNCTIONAL CONSEQUENCES OF TRANSCRIPTIONAL ENHANCER ACTIVATION ON ALTERNATIVE SPLICING DURING EMT | 2017 |
89 | IntScOmics | A single-cell genomics approach integrating gene expression, lineage, and physical interactions | 2018 |
90 | LIMA | Liquid biopsies and Imaging for improved cancer care | 2018 |
91 | transtryp | Structural differences in mRNA translation machineries between eukaryotic pathogens and their mammalian hosts | 2018 |
92 | MODVASC | Endothelial RNA Modifications in Vascular Homeostasis and Disease | 2018 |
93 | mRNP-PackArt | Nuclear mRNA Packaging and mRNP Architecture | 2018 |
94 | LSO | Liver Spatial Omics | 2018 |
95 | TCAPS | mRNA cap regulation and function in CD8 T cells | 2018 |
96 | RNActivate | Optochemical control of cell fate by activation of mRNA translation | 2018 |
97 | SplicEcomplex | Deciphering the structure and dynamics of the early spliceosome assembly | 2018 |
98 | NovoFold | De novo protein discovery as a tool for understanding the folding conundrum | 2019 |
99 | NutriCoRe | An RNA-based mechanism for the nutritional control of bacterial DNA replication initiation | 2018 |
100 | PLANT-RNA-MET | A newly discovered role for mRNA methylation in controlling plant gene expression | 2018 |
101 | RNAmpMax | Maximization of amplification of next-generation RNA replicon vaccines through synergistic molecular and formulation design | 2019 |
102 | scTRYPseq | Understanding the initiation virulence gene expression in African trypanosomes | 2019 |
103 | SPLICEOSACT | Biochemical and CryoEM studies of spliceosome activation. | 2019 |
104 | RNAfate | Identifying RNA fate checkpoints by resolving the high-resolution spatiotemporal binding dynamics of CBC containing complexes | 2019 |
105 | Neuronetmir | Role of miR-129-5p and Rbfox1 crosstalk in neural network homeostasis | 2018 |
106 | TRANSREG | Dissecting the role of Translational Regulation in Tumorigenesis | 2018 |
107 | SUMMIT | Stepping Up mRNA Mutanome Immunotherapy | 2018 |
108 | VIRUSES AND RNA | RNA regulation during viral infection | 2019 |
109 | RiboInflam | Assessing the role of ribosomes and mRNA translation in shaping the inflammatory response | 2019 |
110 | Neuro-UTR | Mechanism and functional impact of ultra-long 3’ UTRs in the Drosophila nervous system | 2019 |
111 | TransTempoFold | A need for speed: mechanisms to coordinate protein synthesis and folding in metazoans | 2019 |
112 | Neurovulnerability | Molecular mechanisms underlying selective neuronal death in motor neuron diseases | 2019 |
113 | GlyCan | Innovative Glycan-based analysis for Cancer diagnostics | 2019 |
114 | TraffikGene | Peptide Dynamic Amphiphiles for Gene Therapy and Macromolecular Delivery | 2019 |
115 | PATRES-MDS | Pathogenesis and treatment of splicing factor mutant myelodysplastic syndromes | 2019 |
116 | TERMINATOR | Ribosomal frameshifts as a novel mechanism to control RNA turnover in stress | 2019 |
117 | LEVERAGE mRNA | Laboratory Evolution of Virus-likE pRotein cAGes for Eukaryotic mRNA delivery | 2019 |
118 | BactRNA | Bacterial small RNAs networks unravelling novel features of transcription and translation | 2019 |
119 | CVD in RA | Mechanistic links between rheumatoid arthritis and cardiovascular complications: investigation on inflammation induced alterations in induced pluripotent stem cell-derived cardiomyocytes | 2020 |
120 | TargetGBM | Generating a targeted, brain-permeable and stable polymeric nanoparticle for systemic gene delivery to glioblastoma | 2019 |
121 | mRNAstress | Investigating the molecular mechanisms of translational reprogramming during cellular stress | 2020 |
122 | EXPERT | EXpanding Platforms for Efficacious mRNA Therapeutics | 2019 |
123 | INSIGHT EU | INSIGHT FOR EYESIGHT – Novel mRNA medicines for eye disease | 2019 |
124 | mRNA NanoDeli | Application of RNA nanotechnology for delivery of mRNA therapeutics | 2019 |
125 | SLAM-Dx | Diagnostic drug response-profiling using SLAMseq | 2019 |
126 | AXONENDO | Endosomal control of local protein synthesis in axons | 2020 |
127 | OBSERVE | Overcoming cellular barriers to therapeutic RNA delivery using extracellular vesicles | 2020 |
128 | DYNOME | Barcoding gene expression dynamics at single-molecule resolution | 2020 |
129 | SILENT | Silent mutations in cancer | 2020 |
130 | MyeRIBO | Deconstructing the Translational Control of Myelination by Specialized Ribosomes | 2020 |
131 | TOR in acTIon | TRANSLATION INITIATION CONTROL IN PLANTS: THE ROLE OF TOR (TARGET OF RAPAMYCIN) | 2020 |
132 | miRanDa | microRNA assay system based on self-assembled nanoscale DNA origami arrays | 2021 |
133 | POL2-TERM | Structural basis of co-transcriptional pre-mRNA 3’-end processing | 2020 |
134 | SupraRNA | A Comprehensive Supramolecular Approach for an RNA vaccine for Influenza A (H1N1) | 2020 |
135 | TETCOLON | Dissecting the role of the epigenetic regulator TET2 in colorectal cancer | 2020 |