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Horizon2020 projects coordinated by "KAROLINSKA INSTITUTET"

# project acronym  year  total cost  totalcontribution 
1 SMART2D A people-centred approach through Self-Management and Reciprocal learning for the prevention and management of Type-2-Diabetes 2015 3˙344˙981.00 3˙344˙979.00
2 GLIOVAC Validation of a conceptually new treatment for glioblastoma multiforme with an IP protected small molecule 2015 149˙693.00 149˙693.00
3 GUTILC3 Cell-cell interactions critical to ILC3 function in the human gut 2015 173˙857.00 173˙857.00
4 EDC-MIXRISK Integrating Epidemiology and Experimental Biology to Improve Risk Assessment of Exposure to Mixtures of Endocrine Disruptive Compounds 2015 6˙223˙330.00 6˙223˙330.00
5 VECTORIGAMI DNA Origami for drug delivery 2015 173˙857.00 173˙857.00
6 ALLELIC REGULATION Revealing Allele-level Regulation and Dynamics using Single-cell Gene Expression Analyses 2015 1˙923˙060.00 1˙923˙060.00
7 PROGSY Prosaposin and GPR37 in synucleinopathies 2015 1˙950˙033.00 1˙950˙033.00
8 RVD3-RAVIS Novel Resolvin D3: its Role and Actions in the Resolution of Aortic Valvular Inflammation and Stenosis 2015 185˙857.00 185˙857.00
9 SYDAD Synaptic Dysfunction in Alzheimer Disease 2015 3˙846˙736.00 3˙846˙736.00
10 CODIC COmmercializing first-in-class dCTPase Inhibitors for treatment of hematological Cancers 2016 150˙000.00 150˙000.00
11 BOOSTB4 Boost Brittle Bones Before Birth 2016 8˙378˙755.00 6˙608˙754.00
12 COSYN Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders 2016 6˙000˙000.00 5˙925˙000.00
13 DYNASPACER Molecular Mechanisms of Dynamic and Spatial Control of Eph Receptors clustering 2016 185˙857.00 185˙857.00
14 POLYDRUG DISCOVERY Discovery of anticancer polymeric drugs that mimic the action of TRAIL 2016 173˙857.00 173˙857.00
15 NORVAS Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease 2016 1˙493˙125.00 1˙493˙125.00
16 SMILED Skeletal Muscle Inflammation: ambivalent roles in Exercise and Diabetes 2016 185˙857.00 185˙857.00
17 SMARTCUBES An innovative class of nanoparticles (“SmartCubes”) for the targeted delivery of protein therapeutics 2016 185˙857.00 185˙857.00
18 PREVENTSTOCAN Understanding microbe-induced stomach cancer – the key to a workable strategy for worldwide prevention 2016 1˙941˙531.00 1˙941˙531.00
19 BORN-IMMUNE Shaping of the Human Immune System by Primal Environmental Exposures In the Newborn Child 2016 1˙422˙338.00 1˙422˙338.00
20 LOCOMOTORINTEGRATION Functional connectome of brainstem circuits that control locomotion 2016 2˙500˙000.00 2˙500˙000.00
21 TAROX Targeting oxidative repair proteins for treatment of cancer and inflammation 2016 2˙279˙406.00 2˙279˙406.00
22 TRANSREAD Restoration of tumor suppressor function by induction of translational read-through of premature termination codons - a strategy for improved cancer therapy 2016 2˙480˙889.00 2˙480˙889.00
23 EPISCOPE Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis 2016 1˙895˙155.00 1˙895˙155.00
24 NEUROGENESIS Exploration and promotion of neurogenesis in the adult brain 2016 2˙500˙000.00 2˙500˙000.00
25 PERICYTESTROMA Pericyte-derived tumor stroma – a target for cancer therapy 2016 185˙857.00 185˙857.00
26 MICRO-MACRO-ILC Dissecting the human microbiota-macrophage-innate lymphoid cell crosstalk in the lung 2016 185˙857.00 185˙857.00
27 RAPID Chromatin dynamics resolved by rapid protein labeling and bioorthogonal capture 2017 1˙846˙360.00 1˙846˙360.00
28 TICKLE ME Self and others in the sensorimotor system: a computational neuroanatomy of sensory attenuation 2017 173˙857.00 173˙857.00
29 MULTIPLEMS Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine 2017 15˙041˙259.00 14˙721˙453.00
30 MULTI-SIP HYDROGEL A multifunctional self-immolative hydrogel for accelerating the healing of chronic wounds 2017 173˙857.00 173˙857.00
31 BETASCREEN Validation of an in vivo translational medicine approach for the treatment of diabetes and diabetes complications 2017 149˙365.00 149˙365.00
32 MITOMETHYLOME Mitochondrial methylation and its role in health and disease 2017 1˙499˙999.00 1˙499˙999.00
33 RNAATHD Development of a high-resolution method to monitor structural changes of regulatory RNAs and therapeutic oligo-nucleotides directly in-cell. 2017 185˙857.00 185˙857.00
34 NOVITREP Novel viral therapy through targeting DNA repair 2017 150˙000.00 150˙000.00
35 PAINCELLS Decomposition of pain into celltypes 2017 2˙443˙952.00 2˙443˙952.00
36 TGDNL Mechanisms of cellular fatty acid homeostasis 2017 265˙059.00 265˙059.00
37 CELLTRACK Cellular Position Tracking Using DNA Origami Barcodes 2017 1˙923˙262.00 1˙923˙262.00
38 HEPASPHER Mimicking liver disease and regeneration in vitro for drug development and liver transplantation 2017 2˙413˙449.00 2˙413˙449.00
39 RTCURE Rheuma Tolerance for Cure 2017 13˙846˙865.00 6˙000˙000.00
40 MIRA Characterizing Microbe-specific Immune Responses in the pathogenesis of Autoimmunity 2017 173˙857.00 173˙857.00
41 5D HEART PATCH A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy 2017 2˙149˙227.00 2˙149˙227.00
42 TRIBAL A TRranslational approach to Identify Biomarkers for Asthma and Lung function impairment 2017 1˙500˙000.00 1˙500˙000.00
43 GENOMIS Illuminating GENome Organization through integrated MIcroscopy and Sequencing 2018 1˙499˙808.00 1˙499˙808.00
44 MTDNA-CURE Treating mitochondrial disease caused by pathogenic mtDNA mutations 2018 2˙500˙000.00 2˙500˙000.00
45 NANO TRACTION Nano Traction 2018 173˙857.00 173˙857.00
46 SELFIEV2.0 Identifying the neuronal basis of self-concept in the human medial prefrontal and medial temporal brain regions 2018 265˙059.00 265˙059.00
47 PROMETHEUS Flame nanoengineering for antibacterial medical devices 2018 1˙812˙500.00 1˙812˙500.00
48 PREVENT RA Towards prevention of autoimmune diseases: the case of rheumatoid arthritis 2018 2˙000˙000.00 2˙000˙000.00
49 CLINGEN-PSYCHTX Identifying Clinical, Demographic, and Genomic Risk Factors for Treatment-Resistant Psychiatric Disorders 2018 185˙857.00 185˙857.00
50 SOLO Single cell omics of the Oligodendrocyte Lineage in develOpment and disease 2018 173˙857.00 173˙857.00
51 REPROGRAM-DIABETES In vivo drug discovery for cellular reprogramming to β-cells – towards a future regenerative therapy for diabetes 2018 1˙999˙968.00 1˙999˙968.00
52 NEVULA Understanding selective neuronal vulnerability in Alzheimer’s disease 2018 247˙059.00 247˙059.00
53 MEGAALS Unravelling the Interplay between Metabolism, Gut Microbiome and Adaptive Immunity in Amyotrophic Lateral Sclerosis 2018 1˙499˙196.00 1˙499˙196.00
54 IMMUNEDIVERSITY Defining of human adaptive immune gene diversity and its impact on disease 2018 2˙500˙000.00 2˙500˙000.00
55 TOPSPEC Next generation precision antibody profiling - from science fiction to reality 2019 3˙991˙500.00 3˙991˙500.00
56 TICK THANK Tick-borne encephalitis Targeted by Human Active NK cells 2019 185˙857.00 185˙857.00
57 CL_EXOCYTOSIS “Molecular dissection of cytotoxic lymphocyte exocytosis 2019 173˙857.00 173˙857.00
58 SELF-UNITY The Unity of the Bodily Self 2019 2˙583˙560.00 2˙583˙560.00
59 SKINTRMDEEP Tissue Resident Memory (Trm) CD8+ T cells: Genome-wide dissection of cellular differentiation and heterogeneity 2019 173˙857.00 173˙857.00
60 SCHIZTYPE Brain cell type-specific interactions and schizophrenia 2019 2˙064˙414.00 2˙064˙414.00
61 ARTSILK Novel approaches to the generation of artificial spider silk superfibers 2019 2˙000˙000.00 2˙000˙000.00
62 EPI4MS Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis 2019 1˙998˙798.00 1˙998˙798.00
63 TERMINATOR Ribosomal frameshifts as a novel mechanism to control RNA turnover in stress 2019 191˙852.00 191˙852.00
64 PCINBC Plasma cell heterogeneity and dynamics in patient tumors 2019 203˙852.00 203˙852.00
65 BRAINTIME Molecular atlas of the brain across the human lifespan 2020 4˙328˙051.00 4˙328˙051.00
66 EYELETS A regenerative medicine approach in diabetes. 2020 2˙500˙000.00 2˙500˙000.00
67 ALERT Action Leveraging Evidence to Reduce perinatal morTality and morbidity in sub-Saharan Africa 2020 3˙999˙976.00 3˙999˙976.00
68 HEAP Human Exposome Assessment Platform 2020 11˙996˙515.00 11˙996˙515.00
69 VIVA Vaccine development against variable pathogens 2020 1˙750˙000.00 1˙750˙000.00
70 TROYCAN Redefining the esophageal stem cell niche – towards targeting of squamous cell carcinoma 2020 1˙483˙389.00 1˙483˙389.00
71 MACINNASH Revealing the contribution of liver macrophage populations to NASH in insulin resistance 2020 1˙999˙781.00 1˙999˙781.00
72 INPRESS International Pregnancy Safety Study 2020 219˙875.00 219˙875.00
73 SYNKIT Synthetic Natural Killer Cells for Immunotherapy 2020 191˙852.00 191˙852.00
74 GUT-SEQ Single-cell analysis of intestinal lymphocytes reveals targets for treatment of inflammatory bowel disease 2020 1˙500˙000.00 1˙500˙000.00
75 SCSC The molecular diversity of regeneration in the zebrafish spinal cord 2020 191˙852.00 191˙852.00
76 HUMANE Transcriptional characterization of human postnatal and adult neural progenitors and of the stem cell niches. 2020 203˙852.00 203˙852.00
77 IMAP Imaging tumor vessels as a marker for p53 mutation status in cancer 2020 203˙852.00 203˙852.00
78 MITAFTERVIT Unravelling maintenance mechanisms of immune tolerance after termination of venom immunotherapy by means of clonal mast cell diseases 2020 191˙852.00 191˙852.00

More Horizon 2020 projects

The Institution KAROLINSKA INSTITUTET has been involved also in the following Horizon 2020 projects.